63028-01-3

Upstream product

• 64-17-5 ethanol 
• 36049-78-2 2-iodooctane 
• 111-66-0 oct-1-ene 
• 638-45-9 1-Iodohexane 
• 23269-46-7 1-(1-ethoxyethyl)-1H-benzo[d][1,2,3]triazole 
• 201230-82-2 carbon monoxide 

Downstream Products

• 32263-64-2 7-(benzyloxy)-3,4-dihydronaphthalen-1(2H)-one 
• 141083-24-1 1[[(4-chloro-2-fluoro-5-isopropoxyphenyl)amino]carbonyl]1,2,3,6-tetra hydro-2-pyridinecarboxylic acid 

Relevant academic research and scientific papers

Selective synthesis of 2-ethoxy alkanes through ethoxylation of 1-alkenes with bioethanol over zeolite beta catalyst in a liquid phase continuous process

1-Hexene was ethoxylated with ethanol and ethanol-water mixtures mimicking bioethanol in a liquid phase, continuous flow process over a fixed bed of zeolite beta catalyst at a reaction temperature of 423 K and a pressure of 6 MPa. The selectivity for ethoxy alkanes on a hexene basis exceeded 90%. GC-MS, 1H & 13C-NMR and 13C DEPT NMR confirmed the main reaction products to be 2-ethoxy hexane and 3-ethoxy hexane in molar ratio 20:1. Side products were diethyl ether from ethanol and dodecenes and hexanol from 1-hexene. Under optimized reaction conditions, the catalyst was stable for at least 14 hours on-stream. The 2-ethoxylation activity of 1-alkenes by zeolite beta was confirmed in reactions with 1-octene and 1-decene. 1-Alkenes can be synthesized out of biomass via conversion into synthesis gas and the Fischer-Tropsch process. The here presented ethoxylation process could contribute green chemicals to the diesel pool and presents a pathway for synthesis of high boiling solvents.

Addition of Benzotriazole to Vinyl Ethers. Chemistry of the Adducts

Benzotriazole adds readily to ethyl vinyl ether, to 2,3-dihydrofuran, and to 3,4-dihydro-2H-pyran to form the respective α-benzotriazolyl ethers.Reactions of benzotriazole with α-methoxy derivatives of tetrahydrofuran and tetrahydropyran give similar products by substitution of benzotriazolyl for the methoxy groups.The corresponding adducts of benzotriazole and vinyl acetates are unstable and eliminate acetate anion to form geminal bis(benzotriazolyl)alkanes.The products show benzotriazol-1-yl to -2-yl isomerization. α-Benzotriazolyl derivatives of tetrahydrofuran and tetrahydropyran react with phenyl- and alkynyl-magnesium reagents to give the respective α-phenyl or α-alkynyl cycloethers.Alkylmagnesium halides by contrast attack the benzotriazolyl N-3 atom of these adducts and open the tetrahydropyranyl ring with formation of an N,N'-disubstituted o-phenylenediamine. 1H and 13C NMR spectra of the products are discussed.