63031-38-9Relevant academic research and scientific papers
Design, green synthesis and pharmacological evaluation of novel 5,6-diaryl-1,2,4-triazines bearing 3-morpholinoethylamine moiety as potential antithrombotic agents*
Tamboli, Riyaj S.,Giridhar, Rajani,Gandhi, Hardik P.,Kanhed, Ashish M.,Mande, Hemant M.,Yadav, Mange Ram
, p. 704 - 713 (2016/07/07)
The aim of this research work was to investigate a series of novel 5,6-diaryl-1,2,4-triazines (3a–3q) containing 3-morpholinoethylamine side chain, and to address their antiplatelet activity by in vitro, ex vivo and in vivo methods. All compounds were syn
Room-temperature ionic liquid-DMSO promoted and improved one-pot synthesis of 5,6-diaryl-1,2,4-triazines
Tamboli, Riyaj S.,Giridhar, Rajani,Mande, Hemant M.,Shah, Shailesh R.,Yadav, Mange Ram
supporting information, p. 2192 - 2204 (2014/07/07)
An improved and rapid one-pot synthesis of 5,6-diarylsubstituted-1,2,4- triazines in a mixture of room-temperature ionic liquid 1,3-dibutylimidazolium bromide [Bbim]+Br- and dimethylsulfoxide (DMSO) is described without the need for
In vitro antitumor activity evaluation of some 1,2,4-triazine derivatives bearing piperazine amide moiety against breast cancer cells
Yurtta, Leyla,Demirayak, eref,Ilgin, Sinem,Atli, ?zlem
, p. 6313 - 6323 (2015/01/09)
A series of 1,2,4-triazine derivatives bearing piperazine amide moiety has been synthesized and investigated for their potential anticancer activities. 1-[4-(5,6-Bis(4-subtituted phenyl)-1,2,4-triazin-3-yl)piperazin-1-yl]-2-[4-(3-substituted phenyl)pipera
Microwave-assisted synthesis and anticonvulsant activity of 5,6-bisaryl-1,2,4-triazine-3-thiolderivatives
Irannejad, Hamid,Naderi, Nima,Emami, Saeed,Ghadikolaei, Roja Qobadi,Foroumadi, Alireza,Zafari, Tina,Mazar-Atabaki, Ali,Dadashpour, Sakineh
, p. 2503 - 2514 (2014/05/06)
A series of 5,6-bisaryl-1,2,4-triazine-3-thiol derivatives were synthesized through microwave-promoted chemistry by condensation of the aromatic 1,2-diketones and thiosemicarbazide in a mixed green solvent. Subsequently, S-alkylation of 1,2,4-triazine-3-t
Diaryl-pyrazine derivatives affecting GABA binding
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, (2008/06/13)
This invention relates to certain amino-5,6-diarylpyrazines useful as activators of GABA and benzodiazepine binding.
1,2,4-Triazine Chemistry. 10. Dihydro-1,2,4-triazines: Structural Studies of 5,6-Diaryldihydro-1,2,4-triazines through the Reactions with Dimethyl Acetylenedicarboxylate
Sasaki, Tadashi,Minamoto, Katsumaro,Harada, Katsuhiko
, p. 4587 - 4593 (2007/10/02)
Sodium borohydride reduction of 3-(methylthio)-5,6-diphenyl- (1a), 3-(methylthio)-5,6-ditolyl- (1c), 3-(methylthio)-5,6-dianisyl- (1e), and 3-(methylthio)-5,6-bis(p-chlorophenyl)-1,2,4-triazine (1g) afforded the corresponding 2,5-dihydro-1,2,4-triazines (
5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents
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, (2008/06/13)
A method of treating inflammation which utilizes topically-active 5,6-diaryl-1,2,4-triazines having the formula, STR1 wherein R is hydrogen or --(X)n R1, in which X is either O or S, n is an integer which is either 0 or 1, and R
5,6-DIARYL-1,2,4-TRIAZINES
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, (2008/06/13)
5,6-Diaryl-1,2,4-triazines, topically-active anti-inflammatory agents, having the formula, STR1 wherein R is hydrogen or --(X)n R1, in which X is either O or S, n is an integer which is either 0 or 1, and R1 is C1/su
