6310-49-2Relevant articles and documents
Covalent Probes for Aggregated Protein Imaging via Michael Addition
Wan, Wang,Huang, Yanan,Xia, Qiuxuan,Bai, Yulong,Chen, Yuwen,Jin, Wenhan,Wang, Mengdie,Shen, Di,Lyu, Haochen,Tang, Yuqi,Dong, Xuepeng,Gao, Zhenming,Zhao, Qun,Zhang, Lihua,Liu, Yu
, p. 11335 - 11343 (2021/04/19)
Covalent chemical reactions to modify aggregated proteins are rare. Here, we reported covalent Michael addition can generally occur upon protein aggregation. Such reactivity was initially discovered by a bioinspired fluorescent color-switch probe mimickin