6310-49-2Relevant academic research and scientific papers
Covalent Probes for Aggregated Protein Imaging via Michael Addition
Wan, Wang,Huang, Yanan,Xia, Qiuxuan,Bai, Yulong,Chen, Yuwen,Jin, Wenhan,Wang, Mengdie,Shen, Di,Lyu, Haochen,Tang, Yuqi,Dong, Xuepeng,Gao, Zhenming,Zhao, Qun,Zhang, Lihua,Liu, Yu
, p. 11335 - 11343 (2021/04/19)
Covalent chemical reactions to modify aggregated proteins are rare. Here, we reported covalent Michael addition can generally occur upon protein aggregation. Such reactivity was initially discovered by a bioinspired fluorescent color-switch probe mimickin
