6311-90-6

Basic information

• Product Name: 2-(2-PYRROLIDINOETHYL)PYRIDINE
• Synonyms: 2-(2-pyrrolidin-1-ylethyl)pyridine
• CAS NO: 6311-90-6
• Molecular Formula: C11H16N2
• Molecular Weight: 176.2636
• Mol File: 6311-90-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 260.2°C at 760 mmHg
• Flash Point: 111.2°C
• Appearance: /
• Density: 1.029g/cm³
• Vapor Pressure: 0.0124mmHg at 25°C
• Refractive Index: 1.542
• CAS DataBase Reference: 2-(2-PYRROLIDINOETHYL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-PYRROLIDINOETHYL)PYRIDINE(6311-90-6)
• EPA Substance Registry System: 2-(2-PYRROLIDINOETHYL)PYRIDINE(6311-90-6)

Safety Data

• Hazardous Substances Data: 6311-90-6(Hazardous Substances Data)

Usage

Pyridine ring

A six-membered aromatic ring with one nitrogen atom This is the backbone of the 2-(2-pyrrolidinoethyl)pyridine molecule.

Pyrrolidinoethyl group

A five-membered cyclic amine group attached to the pyridine ring This group is responsible for the compound's basicity and reactivity.

Building block for other chemical compounds

2-(2-pyrrolidinoethyl)pyridine is often used as a starting material in organic synthesis to create a variety of other chemical compounds.

Reagent in pharmaceuticals, agrochemicals, and specialty chemicals

The compound is commonly used as a reagent in the preparation of various commercial products, including pharmaceuticals, agrochemicals, and other specialty chemicals.

Useful for the development of new compounds and materials

The chemical structure and properties of 2-(2-pyrrolidinoethyl)pyridine make it a valuable building block for the development of new compounds and materials in a variety of industries.

InChI:InChI=1/C11H16N2/c1-2-7-12-11(5-1)6-10-13-8-3-4-9-13/h1-2,5,7H,3-4,6,8-10H2

Upstream product

• 123-75-1 pyrrolidine 
• 100-69-6 2-vinylpyridine 
• 138428-37-2 2-(pyridin-2-yl)ethyl methanesulfonate 
• 103-74-2 2-(2-Hydroxyethyl)pyridine 
• 109-06-8 α-picoline 

Downstream Products

• 25082-00-2 2-(2-Pyrrolidino-ethyl)-piperidin 

Relevant articles and documents

Hydroamination of 2-vinylpyridine, styrene, and isoprene with pyrrolidine catalyzed by alkali and alkaline-earth metal complexes

The complexes (dpp-bian)Mg(thf)3, (dpp-bian)Ca(thf)4 and (dpp-bian)Mg(pyr)3 (dpp-bian is the 1,2-bis[(2,6-diisopropylphenyl)imino]acenaphthene dianion; pyr is the pyrrolidine) catalyze the addition of pyrrolidine to 2-viny

Aza-Michael-type addition reaction catalysed by a supported ionic liquid phase incorporating an anionic heteropoly acid

In this work, we have obtained substituted amines under mild conditions in good yields using the Aza-Michael-type addition of various amines to vinyl compounds catalysed by a supported ionic liquid incorporating an anionic heteropoly acid. Different catalysts, including Lewis acids, Br?nsted acids and heteropoly acids were investigated in which heteropoly acids having dual Br?nsted and Lewis acid characteristics were excellent catalysts. The ionic liquid incorporating a polytungstate anion supported on magnetic diatomaceous earth as a magnetically separable heterogeneous catalyst offered the best results in terms of yield. The solid nanocatalyst was easily removed with a magnet.

7-Azabicyclo[2.2.1]heptane as a scaffold for the development of selective sigma-2 (σ2) receptor ligands

A series of N-substituted 7-azabicyclo[2.2.1]heptanes (12-17 and 22-25) and similarly substituted pyrrolidines (32-36 and 41-44) were synthesized as sterically-reduced, achiral analogs of adamantane- and trishomocubane-derived σ ligands. In vitro competition binding assays against σ receptors revealed that arylalkyl N-substituents conferred selectivity for the σ2 subtype, while alicyclic or polycarbocyclic substituents imparted high affinity for both subtypes. The σ2 binding and subtype selectivities of N-arylalkyl-7-azanorbornanes was generally greater than the analogously-substituted pyrrolidines, indicating that steric bulk and conformational restriction around the nitrogen atom are likely important for subtype discrimination.