63124-72-1Relevant academic research and scientific papers
Double gold-catalysed annulation of indoles by enynones
Heffernan, Stephen J.,Tellam, James P.,Queru, Marine E.,Silvanus, Andrew C.,Benito, David,Mahon, Mary F.,Hennessy, Alan J.,Andrews, Benjamin I.,Carbery, David R.
supporting information, p. 1149 - 1159 (2013/05/22)
The gold-catalysed double functionalisation of indoles is presented. Enynones are used to annulate indoles via a double sodium tetrachloroaurate- catalysed process involving a mixture of C-H activation and alkyne activation modes of promotion. Good yields
Palladium-catalyzed acylation and/or homo-coupling of aryl- and alkyl-acetylenes
Perrone, Serena,Bona, Fabio,Troisi, Luigino
experimental part, p. 7386 - 7391 (2011/10/09)
Allyl or benzyl halides, through a Pd(0)-catalyzed reaction and under CO pressure, generate acyl-palladium/halides that, in the presence of a base and an aryl- and alkyl-acetylene, undergo nucleophilic acyl substitution giving conjugated acetylenic ketones. Diynes, resulting from alkyne/alkyne homo-coupling, were instead the main products in reactions performed without allyl or benzyl halides. Moreover, dimerization, trimerization, and cyclotrimerization reactions of acetylenes were observed in reaction carried out even without base.
