63133-68-6

Upstream product

• 100-52-7 benzaldehyde 
• 108-42-9 3-chloro-aniline 
• 698-16-8 benzohydroximoyl chloride 
• 932-90-1 Benzaldoxime 
• 52379-49-4 N₁-(3-chlorophenyl)-1-benzenecarboximidamide 
• 873-67-6 benzonitrile oxide 

Downstream Products

• 1019-90-5 5-chloro-2-phenyl-1,3-benzoxazole 
• 63105-06-6 3-(3-chloro-phenyl)-4-phenyl-3H-[1,2,3,5]oxathiadiazole 2-oxide 

Relevant academic research and scientific papers

Synthesis and substituent effect study on 13C NMR chemical shifts of 4-(substitue-phenyl)-6-methyl-3-phenyl-4H-1,2,4-oxadiazin-5(6H)-one

The twelve novel 4-(substituted-phenyl)-6-methyl-3-phenyl-4H-1,2,4-oxadiazin-5(6H)-one derivatives were synthesized by the reactions of N-Substituted-phenyl-benzamide oximes with 2-bromopropionyl chloride. The synthesized 1,2,4-oxadiazin-5-one derivatives

Iodine Promoted One-Pot Synthesis of 2-Aryl Benzoxazoles from Amidoximes via Oxidative Cyclization and Ring Contraction

A molecular I2-promoted one-pot synthesis of 2-aryl benzoxazoles has been developed by using amidoximes rather than the limited 2-aminophenols or 2-haloamides as substrates. The amidoxime substrates provided unique and efficient strategies for converting readily available aniline and benzaldehyde precursors into valuable chemicals. This transformation proceeded smoothly under transition-metal-free conditions through a sequential oxidative cyclization and ring contraction, and provided a potential route for introducing certain groups at any site of the scaffold.

13C NMR substituent-induced chemical shifts in 4-(substituted phenyl)-3-phenyl-1,2,4-oxadiazol-5(4H)-ones (thiones)

In the present, study mostly novel ten 4-(substituted phenyl)-3-phenyl-1,2,4-oxadiazol-5(4H)-ones and ten 4-(substituted phenyl)-3-phenyl-1,2,4-oxadiazol-5(4H)-thiones were synthesized. These oxadiazole derivatives were characterized by IR, 1H