631914-72-2

Usage

Uses

Used in Agricultural Industry:
TERT-BUTYL (3,6-DICHLOROPYRIDAZIN-4-YL)METHYLCARBAMATE is used as a pesticide or herbicide for its ability to effectively manage and control pests and weeds. It is valued for its targeted action on specific pests while maintaining relative safety for other plants and animals, thus contributing to crop protection and yield enhancement.
However, it is crucial to handle this chemical with care due to its potential health risks and environmental hazards if used improperly or exposed inappropriately. Proper application and safety measures are essential to mitigate any adverse effects and ensure the sustainability of agricultural practices.

InChI:InChI=1/C10H13Cl2N3O2/c1-10(2,3)17-9(16)15(4)6-5-7(11)13-14-8(6)12/h5H,1-4H3

Upstream product

• 4530-20-5 BOC-glycine 
• 141-30-0 3,6-dichlorpyridazine 

Relevant academic research and scientific papers

MONOCYCLIC AGONISTS OF STIMULATOR OF INTERFERON GENES STING

The invention provides compounds having STimulator of INterferon Genes (STING) agonistic bioactivity that can be used in the treatment of tumors in patients afflicted therewith. The compounds are of formula (IA), formula (I), and formula (II): wherein the various substituents are as defined herein. Ring A is a 5- or 6- membered heteroaryl comprising 1, 2, or 3 N atoms, unsubstituted or substituted with 1, 2, or 3 groups as defined herein. Compounds for practice of a method of the invention can be delivered via oral delivery for systemic exposure, as well as delivered intratumorally. Antitumor therapy using a compound of formula (I) can further comprise administration of an effective dose of an immunecheckpoint targeting drug.

CYCLOPROPANE DERIVATIVE AND DRUG CONTAINING SAME

A compound represented by the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof has superior TRPA1 antagonist activity, and the compound or a pharmaceutically acceptable salt thereof is useful for the prophylaxis or treatment of diseases involving TRPA1 antagonist and TRPA1.

HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME

The present invention provides a compound represented by the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof. The compound has a superior TRPA1 antagonist activity, and can provide a medicament useful for the prophylaxis or treatment of diseases involving TRPA1 antagonist and TRPA1.

Use of N-Protected Amino Acids in the Minisci Radical Alkylation

(Equation presented) The Minisci radical alkylation has been demonstrated on a range of commercially available glycine derivatives and proceeds in good to high yield. When extending the reaction to other amino acids, competitive oxidation of the initially formed radical was overcome by using the phthalimide protecting group.