6322-01-6

Basic information

• Product Name: 1-AMINO-3-DIETHYLAMINO-2-PROPANOL
• Synonyms: TIMTEC-BB SBB010310;1-AMINO-3-DIETHYLAMINO-2-PROPANOL;IFLAB-BB F2137-0019;Einecs 228-676-4
• CAS NO: 6322-01-6
• Molecular Formula: C₇H₁₈N₂O
• Molecular Weight: 146.23
• EINECS: 228-676-4
• Mol File: 6322-01-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 265.87°C (rough estimate)
• Flash Point: 88.7°C
• Appearance: /
• Density: 0.9310
• Vapor Pressure: 0.0201mmHg at 25°C
• Refractive Index: 1.4650 (estimate)
• CAS DataBase Reference: 1-AMINO-3-DIETHYLAMINO-2-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AMINO-3-DIETHYLAMINO-2-PROPANOL(6322-01-6)
• EPA Substance Registry System: 1-AMINO-3-DIETHYLAMINO-2-PROPANOL(6322-01-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 6322-01-6(Hazardous Substances Data)

Usage

General Description

1-Amino-3-diethylamino-2-propanol, also known as ADEP, is a chemical compound that belongs to the group of aliphatic amines. It is commonly used as a raw material in the synthesis of pharmaceuticals and other organic compounds. ADEP has a hydroxyl group and two secondary amine groups, making it a versatile molecule for various chemical reactions. It is often used as a chelating agent and as a component in the production of surfactants and detergents. ADEP has a wide range of applications in the chemical and pharmaceutical industries, making it an important and valuable compound in the field of organic chemistry.

InChI:InChI=1/C7H18N2O/c1-3-9(4-2)6-7(10)5-8/h7,10H,3-6,8H2,1-2H3/t7-/m0/s1

Upstream product

• 2917-91-1 glycidyldiethylamine 
• 15285-59-3 1-chloro-3-diethylaminopropan-2-ol 
• 64-17-5 ethanol 
• 19667-37-9 2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione 
• 109-89-7 diethylamine 
• 7664-41-7 ammonia 

Downstream Products

• 525-31-5 7-Chlor-4-(2-hydroxy-3-diethylamino-propylamino)-chinolin 
• 5423-78-9 1-diethylamino-3-(6,7-dichloro-[4]quinolylamino)-propan-2-ol 
• 5431-51-6 1-diethylamino-3-(5,8-dichloro-[4]quinolylamino)-propan-2-ol 
• 20178-56-7 1-diethylamino-3-(2-methoxy-6-nitro-acridin-9-ylamino)-propan-2-ol 
• 93351-93-0 1-(2-amino-anilino)-3-diethylamino-propan-2-ol 
• 113651-41-5 3-(4-methoxy-phenyl)-2-phenyl-propionic acid-(3-diethylamino-2-hydroxy-propylamide) 
• 102471-83-0 2-methoxy-4-nitro-benzoic acid-(3-diethylamino-2-hydroxy-propylamide) 
• 17938-99-7 5-diethylaminomethyl-oxazolidin-2-one 
• 73480-63-4 N-(3-Diethylamino-2-hydroxy-propyl)-2-methylamino-benzamide 
• 87416-04-4 N-(2-Hydroxy-3-diethylaminopropyl)diphenylacetamide 
• 87416-05-5 N-(2-Hydroxy-3-diethylaminopropyl)-α-methoxydiphenylacetamide 
• 111380-69-9 1-(3-Diethylamino-2-hydroxy-propylamino)-4,5-dimethyl-5H-pyrido[4,3-b]indol-8-ol 
• 83200-08-2 2-[3-(N,N-diethylamino)-2-hydroxypropylaminocarbonyl]-3-methoxy-1-phenylindole 

Relevant articles and documents

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3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone derivatives as portein kinase inhibitors

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

Mannich base prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives

The present invention is directed to Mannich base prodrugs of certain 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives that modulate the activity of protein kinases (“PKs”). Pharmaceutical compositions comprising these compounds, methods of treating diseases related to abnormal PK activity utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.