6324-05-6

Basic information

• Product Name: amino[4-(dimethylamino)phenyl]acetic acid
• CAS NO: 6324-05-6
• Molecular Formula: C₁₀H₁₄N₂O₂
• Molecular Weight: 194.2304
• Mol File: 6324-05-6.mol

Chemical Properties

• Boiling Point: 361.9°C at 760 mmHg
• Flash Point: 172.7°C
• Density: 1.219g/cm³
• Vapor Pressure: 7.16E-06mmHg at 25°C
• Refractive Index: 1.609
• CAS DataBase Reference: amino[4-(dimethylamino)phenyl]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: amino[4-(dimethylamino)phenyl]acetic acid(6324-05-6)
• EPA Substance Registry System: amino[4-(dimethylamino)phenyl]acetic acid(6324-05-6)

Safety Data

• Hazardous Substances Data: 6324-05-6(Hazardous Substances Data)

Upstream product

• 126746-23-4 5-(4-dimethylamino-phenyl)-imidazolidine-2,4-dione 
• 63756-72-9 2-(4-(dimethylamino)phenyl)-2-oxoacetic acid 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 41116-24-9 ethyl 2-(4-(dimethylamino) phenyl)-2-oxoacetate 

Relevant articles and documents

Synthesis of Unprotected 2-Arylglycines by Transamination of Arylglyoxylic Acids with 2-(2-Chlorophenyl)glycine

The transamination of α-keto acids with 2-phenylglycine is an effective methodology for directly synthesizing unprotected α-amino acids. However, the synthesis of 2-arylglycines by transamination is problematic because the corresponding products, 2-arylglycines, transaminate the starting arylglyoxylic acids. Herein, we demonstrate the use of commercially available l-2-(2-chlorophenyl)glycine as the nitrogen source in the transamination of arylglyoxylic acids, producing the corresponding 2-arylglycines without interference from the undesired self-transamination process.

7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids

Certain 7-acylamido-3-(1-carboxy-loweralkyl-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids and their salts and easily hydrolyzed esters of the 4-carboxyl group were synthesized and found to be potent antibacterial agents which exhibited good aqueous solubility. In a preferred embodiment the 7-substituent was 2'-aminomethylphenylacetamido.