41116-24-9

Basic information

• Product Name: ETHYL 4-DIMETHYLAMINOBENZOYLFORMATE
• Synonyms: ETHYL 4-DIMETHYLAMINOBENZOYLFORMATE;ETHYL 4-(N,N-DIMETHYLAMINO)BENZOYLFORMATE;Ethyl 2-(4-(dimethylamino)phenyl)-2-oxoacetate;(4-Dimethylaminophenyl)oxoacetic acid ethyl ester
• CAS NO: 41116-24-9
• Molecular Formula: C₁₂H₁₅NO₃
• Molecular Weight: 221.25
• Mol File: 41116-24-9.mol
• Article Data: 9

Chemical Properties

• Melting Point: 92-93°C
• Boiling Point: 343.1°C at 760 mmHg
• Flash Point: 161.3°C
• Appearance: /
• Density: 1.131g/cm³
• Vapor Pressure: 7.18E-05mmHg at 25°C
• Refractive Index: 1.543
• CAS DataBase Reference: ETHYL 4-DIMETHYLAMINOBENZOYLFORMATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-DIMETHYLAMINOBENZOYLFORMATE(41116-24-9)
• EPA Substance Registry System: ETHYL 4-DIMETHYLAMINOBENZOYLFORMATE(41116-24-9)

Safety Data

• Hazardous Substances Data: 41116-24-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H15NO3/c1-4-16-12(15)11(14)9-5-7-10(8-6-9)13(2)3/h5-8H,4H2,1-3H3

Upstream product

• 13190-50-6 4-dimethylaminophenyllithium 
• 95-92-1 oxalic acid diethyl ester 
• 4755-77-5 Ethyl oxalyl chloride 
• 121-69-7 N,N-dimethyl-aniline 
• 7446-70-0 aluminium trichloride 
• 140-89-6 potassium ethyl xanthogenate 
• 2124-31-4 4'-dimethylaminoacetophenone 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 586-77-6 4-bromo-N,N-dimethylaniline 

Downstream Products

• 63756-72-9 2-(4-(dimethylamino)phenyl)-2-oxoacetic acid 
• 619-84-1 p-N,N-dimethylaminobenzoic acid 
• 149302-71-6 (+/-)-1-<4-(dimethylamino)phenyl>-1,2-ethanediol 
• 29884-03-5 2-(4-(dimethylamino)phenyl)glycine 
• 157119-18-1 (4-dimethylamino-phenyl)-oxoacetyl chloride 

Relevant articles and documents

Solution and Solid-State Emission Toggling of a Photochromic Hydrazone

The proliferation of light-activated switches in recent years has enabled their use in a broad range of applications encompassing an array of research fields and disciplines. All current systems, however, have limitations (e.g., from complicated synthesis

Synthesis of Unprotected 2-Arylglycines by Transamination of Arylglyoxylic Acids with 2-(2-Chlorophenyl)glycine

The transamination of α-keto acids with 2-phenylglycine is an effective methodology for directly synthesizing unprotected α-amino acids. However, the synthesis of 2-arylglycines by transamination is problematic because the corresponding products, 2-arylglycines, transaminate the starting arylglyoxylic acids. Herein, we demonstrate the use of commercially available l-2-(2-chlorophenyl)glycine as the nitrogen source in the transamination of arylglyoxylic acids, producing the corresponding 2-arylglycines without interference from the undesired self-transamination process.

Zincation and Magnesiation of Functionalized Silylated Cyanohydrins Using TMP-Bases

Polyfunctional silylated cyanohydrins are readily magnesiated or zincated with TMPMgCl·LiCl or TMP 2 Zn·2MgCl 2 ·2LiCl leading to the corresponding metallated derivatives. These Mg- or Zn-derivatives react with various electrophiles such as benzylic bromides, allylic bromides, acid chlorides, aldehydes, NCCO 2 Et, or MeSO 2 SMe. Subsequently, TBAF-deprotection provides the corresponding keto or 1,2-diketo derivatives.