633-12-5

Basic information

• Product Name: 2,4,6-TRIBROMOBENZOIC ACID
• Synonyms: 2,4,6-TRIBROMOBENZOIC ACID
• CAS NO: 633-12-5
• Molecular Formula: C₇H₃Br₃O₂
• Molecular Weight: 358.81
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 633-12-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 192°C
• Boiling Point: 366.1±42.0 °C(Predicted)
• Appearance: /
• Density: 2.1779 (rough estimate)
• Refractive Index: 1.5438 (estimate)
• Storage Temp.: 2-8°C
• PKA: pK1:1.41 (25°C)
• Water Solubility: 3.5g/L(15 oC)
• CAS DataBase Reference: 2,4,6-TRIBROMOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TRIBROMOBENZOIC ACID(633-12-5)
• EPA Substance Registry System: 2,4,6-TRIBROMOBENZOIC ACID(633-12-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 633-12-5(Hazardous Substances Data)

Usage

General Description

2,4,6-tribromobenzoic acid is a chemical compound with the molecular formula C7H3Br3O2. It is a derivative of benzoic acid and is a white solid at room temperature. 2,4,6-TRIBROMOBENZOIC ACID is primarily used as a flame retardant, especially in plastics, textiles, and building materials. It acts by releasing bromine radicals when exposed to heat, which then interfere with the combustion process. Additionally, 2,4,6-tribromobenzoic acid is also used in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. Due to its bromine content, this compound is considered to be hazardous to the environment and human health, and its use is regulated by various government agencies.

Upstream product

• 861518-86-7 2,4,6-tribromo-benzyl chloride 
• 7697-37-2 nitric acid 
• 7664-93-9 sulfuric acid 
• 100-44-7 benzyl chloride 
• 861605-41-6 3-amino-2,4,6-tribromo-benzaldehyde 
• 147-82-0 2,4,6-tribromoaniline 
• 363598-44-1 (2,4,6-tribromophenyl)trimethylsilane 
• 722540-83-2 (2,4,6-tribromophenyl)triethylsilane 
• 650598-46-2 (2,6-dibromophenyl)triethylsilane 
• 108-36-1 1,3-dibromobenzene 
• 124-38-9 carbon dioxide 
• 634-89-9 1,2,3,5-tetrabromobenzene 
• 615-54-3 1,2,4-tribromobenzene 
• 35851-93-5 2,4,6-tribromobenzonitrile 

Downstream Products

• 22019-75-6 2,4,6-tribromo-benzoyl chloride 
• 14920-88-8 2,4,6-tribromo-benzoic acid methyl ester 
• 22019-73-4 2,4,6-Tribrombenzylalkohol 
• 5947-23-9 2,4,6-tribromo-benzoic acid amide 
• 45859-98-1 2,4,6-tribromobenzaldehyde 
• 611-00-7 2,4-dibromobenzoic acid 
• 14435-76-8 <2,4,6-(2)H3>benzoic acid 
• 71372-05-9 2,4,6-Tribromo-3-nitro-benzoic acid 

Relevant articles and documents

Preparation method of 2,4,6-tribromobenzoic acid

The invention discloses a preparation method of high purity 2,4,6-tribromobenzoic acid. The preparation method is characterized by comprising the following steps: with pure water as a solvent, reacting m-aminobenzoic acid with bromine at 5-10 DEG C for ri

Buttressing Effects Rerouting the Deprotonation and Functionalization of 1,3-Dichloro- and 1,3-Dibromobenzene

A systematic comparison between 1,3-difluorobenzene, 1,3-dichlorobenzene, and 1,3-dibromobenzene did not reveal major differences in their behavior towards strong bases such as lithium diisopropylamide or lithium 2,2,6,6-tetramethyl-piperidide. Thus, all 2,6-dihalobenzoic acids 1 are directly accessible by consecutive treatment with a suitable base and dry ice. In contrast, (2,6-dichlorophenyl)- and (2,6-bromo-phenyl)triethylsilane (2a and 2b) were found to undergo deprotonation at the 5-position (affording acids 3 and, after deprotection, 4), whereas the 1,3-difluoro analog is known to react at the 4-position. The 2,4-dihalobenzoic acids 7 were selectively prepared from either the silanes 2 (by bromination at the 4-position, metalation and carboxylation of the neighboring position, followed by desilylation and debromination) or the 1,3-dihalo-2-iodobenzenes 8 (by base-promoted migration of iodine to the 4-position followed by iodine/magnesium permutation and subsequent carboxylation). Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.