633-12-5

Usage

Uses

Used in Plastics Industry:
2,4,6-TRIBROMOBENZOIC ACID is used as a flame retardant for plastics to enhance their fire resistance. It releases bromine radicals when exposed to heat, which interfere with the combustion process, thereby reducing the risk of fire.
Used in Textile Industry:
In the textile industry, 2,4,6-TRIBROMOBENZOIC ACID is utilized as a flame retardant for fabrics and fibers. It helps to slow down the spread of fire and provides additional safety to clothing, upholstery, and other textile products.
Used in Building Materials:
2,4,6-TRIBROMOBENZOIC ACID is employed as a flame retardant in building materials such as insulation, wall coverings, and carpets. Its inclusion in these materials helps to reduce the risk of fire spread in buildings and provides enhanced safety.
Used in Synthesis of Organic Compounds:
2,4,6-TRIBROMOBENZOIC ACID is used as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. Its unique chemical structure allows for the development of new and effective products in these industries.
However, it is important to note that due to its bromine content, 2,4,6-TRIBROMOBENZOIC ACID is considered hazardous to the environment and human health. As a result, its use is regulated by various government agencies to ensure safety and minimize potential risks.

Upstream product

• 6320-40-7 2,4,6-tribromotoluene 
• 35851-93-5 2,4,6-tribromobenzonitrile 
• 45859-98-1 2,4,6-tribromobenzaldehyde 
• 861518-86-7 2,4,6-tribromo-benzyl chloride 
• 54459-64-2 2,4,6-tribromo-1-(bromomethyl)benzene 
• 6628-84-8 3-amino-2,4,6-tribromobenzoic acid 
• 626-39-1 1,3,5-trisbromobenzene 
• 124-38-9 carbon dioxide 
• 7697-37-2 nitric acid 
• 7664-93-9 sulfuric acid 
• 615-54-3 1,2,4-tribromobenzene 
• 634-89-9 1,2,3,5-tetrabromobenzene 
• 108-36-1 1,3-dibromobenzene 
• 650598-46-2 (2,6-dibromophenyl)triethylsilane 

Downstream Products

• 611-00-7 2,4-dibromobenzoic acid 
• 22019-73-4 2,4,6-Tribrombenzylalkohol 
• 14920-88-8 2,4,6-tribromo-benzoic acid methyl ester 
• 14435-76-8 <2,4,6-(2)H3>benzoic acid 
• 71372-05-9 2,4,6-Tribromo-3-nitro-benzoic acid 
• 22019-75-6 2,4,6-tribromo-benzoyl chloride 
• 5947-23-9 2,4,6-tribromo-benzoic acid amide 
• 45859-98-1 2,4,6-tribromobenzaldehyde 

Relevant academic research and scientific papers

Direct C–H Carboxylation Forming Polyfunctionalized Aromatic Carboxylic Acids by Combined Br?nsted Bases

CO2 fixation into electron-deficient aromatic C–H bonds proceeds with the combined Br?nsted bases LiO-t-Bu and LiO-t-Am/CsF/18-crown-6 (t-Am = CEtMe2) under a CO2 atmosphere to afford a variety of polyfunctionalized aromat

Selective oxidation method for toluene compounds

The invention discloses a selective oxidation method for toluene compounds. The method comprises the following steps: 1, putting a toluene compound represented by a formula (I) shown in the specification, a metalloporphyrin catalyst, an oxidant and a dispersing agent into a ball milling tank, sealing the ball milling tank, carrying out ball milling for 3-24 hours at room temperature and the rotating speed of 100-800 rpm, stopping ball milling once every 1-3 hours in the ball milling process, discharging gas in the ball milling tank, and after the reaction is finished, carrying out post-treatment on the reaction mixture to obtain a product benzoic acid compound represented by a formula (II) shown in the specification. Oxidation conversion of methylbenzene and derivatives thereof is achievedthrough solid-phase ball milling, the reaction mode is novel, the operation is convenient, and the energy consumption is low; an organic solvent and other auxiliaries are not needed, so that use of toxic and harmful organic reagents is effectively avoided, and the method is green and environmentally friendly; the peroxide content is low, and the safety coefficient is high; and benzoic acid and derivatives thereof have high selectivity and meet the social requirements of a green chemical process, an environmental compatibility chemical process and a biological compatibility chemical process inthe prior art.

Preparation method of 2,4,6-tribromobenzoic acid

The invention discloses a preparation method of high purity 2,4,6-tribromobenzoic acid. The preparation method is characterized by comprising the following steps: with pure water as a solvent, reacting m-aminobenzoic acid with bromine at 5-10 DEG C for ri

Buttressing Effects Rerouting the Deprotonation and Functionalization of 1,3-Dichloro- and 1,3-Dibromobenzene

A systematic comparison between 1,3-difluorobenzene, 1,3-dichlorobenzene, and 1,3-dibromobenzene did not reveal major differences in their behavior towards strong bases such as lithium diisopropylamide or lithium 2,2,6,6-tetramethyl-piperidide. Thus, all 2,6-dihalobenzoic acids 1 are directly accessible by consecutive treatment with a suitable base and dry ice. In contrast, (2,6-dichlorophenyl)- and (2,6-bromo-phenyl)triethylsilane (2a and 2b) were found to undergo deprotonation at the 5-position (affording acids 3 and, after deprotection, 4), whereas the 1,3-difluoro analog is known to react at the 4-position. The 2,4-dihalobenzoic acids 7 were selectively prepared from either the silanes 2 (by bromination at the 4-position, metalation and carboxylation of the neighboring position, followed by desilylation and debromination) or the 1,3-dihalo-2-iodobenzenes 8 (by base-promoted migration of iodine to the 4-position followed by iodine/magnesium permutation and subsequent carboxylation). Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.

Extensive halogen scrambling and buttressing effects encountered upon treatment of oligobromoarenes with bases

As a rule, tri-, tetra- and pentahaloarenes readily undergo ortho-lithiation when treated with amide-type bases. However, halogen migration occurs whenever the substrate contains three or more contiguous halogen atoms, provided that at least one of them is bromine or iodine. Dismutation and reduction processes often take place concomitantly. In this manner, a variety of organometallic intermediates may be formed, the driving force always being a decrease in basicity. When no such energy gain can be achieved, a sterically crowded substrate may just turn out to be inert; this was found to be the case with 1,5-dibromo-3-fluoro-2-(trimethylsilyl)benzene, 1,5-dibromo-3-fluoro-2,4-bis(trimethylsilyl)benzene, and 1,5-dibromo-3-fluoro-2,4-diiodobenzene. Buttressing effects are apparently strong enough to prevent expedient deprotonation of those substrates.

The acidifying effects of chlorine and bromine: Little difference

Lithium diisopropylamide deprotonates ortho- and para-bromochlorobenzene randomly at the two halogen adjacent positions. Obviously for steric reasons, the bulkier base lithium 2,2,6,6-tetramethylpiperidide favors the attack in the vicinity of the chlorine rather than the bromine atom to the extent of 2:1. At -75°C, both 2-bromo-3-chlorophenyllithium and 3-bromo-2-chlorophenyllithium isomerize to give 2-bromo-6-chlorophenyllithium. The latter species can be directly generated from 1-bromo-3-chlorobenzene.