633-29-4

Basic information

• Product Name: testosterone 17 beta-carboxylic acid
• Synonyms: testosterone 17 beta-carboxylic acid
• CAS NO: 633-29-4
• Molecular Formula: C₂₀H₂₈O₄
• Molecular Weight: 332.43
• Mol File: 633-29-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 238-240 °C (decomp)(Solv: methanol (67-56-1))
• Boiling Point: 522°C at 760 mmHg
• Flash Point: 283.6°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 4.44E-13mmHg at 25°C
• Refractive Index: 1.583
• PKA: 3.89±0.60(Predicted)
• CAS DataBase Reference: testosterone 17 beta-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: testosterone 17 beta-carboxylic acid(633-29-4)
• EPA Substance Registry System: testosterone 17 beta-carboxylic acid(633-29-4)

Safety Data

• Hazardous Substances Data: 633-29-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H28O4/c1-18-8-5-13(21)11-12(18)3-4-14-15(18)6-9-19(2)16(14)7-10-20(19,24)17(22)23/h11,14-16,24H,3-10H2,1-2H3,(H,22,23)/t14-,15+,16+,18+,19+,20?/m1/s1

Upstream product

• 77881-13-1 17β-cyano-17α-hydroxy-4-androsten-3-one 
• 67-56-1 methanol 
• 152-58-9 Cortexolone 
• 81481-39-2 17α-hydroxy-3-oxo-4-androstene-17-carboxylic acid amide 
• 6762-52-3 20-Hydroxy-21-oxo-pregnadien-<4.17(20)>-on-(3) 

Downstream Products

• 206351-46-4 3-[(3R,3aS,5aS,6R,9aS,9bS)-3-Hydroxy-3a,6-dimethyl-3-(4-nitro-3-trifluoromethyl-phenylcarbamoyl)-7-oxo-dodecahydro-cyclopenta[a]naphthalen-6-yl]-propionic acid 
• 206351-47-5 N-(3'-trifluoromethyl-4'-nitrophenyl)-17α-hydroxy-3-oxo-4-azaandrost-5-ene-17β-carboxamide 
• 206351-45-3 N-(3'-trifluoromethyl-4'-nitrophenyl)-17α-hydroxy-3-oxoandrost-4-ene-17β-carboxamide 

Relevant articles and documents

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Synthesis of N-substituted 3-oxo-17β -carboxamide-4-aza-5α-androstanes and the tautomerism of 3-oxo-4-aza-5-androstenes

An N-aryl-3-oxo-4-aza-5α -androst-1-ene-17β carboxamide and three N-aryl or alkyl substituted 17α -hydroxy-3-oxo-4-aza-5α -androstane-17β -carboxamides were synthesized as antiandrogen candidates from 3-oxoandrost-4-ene-17β - carboxylic acid and androst-4-ene-3,17-dione respectively. The chemo- and stereoselective reduction of 3-oxo-4-aza-5-ene intermediates with formic acid and their tautomerism in a solution of chloroform and methanol were described.