6330-51-4

Basic information

• Product Name: N-Formyl-1-naphthylamine
• Synonyms: N-Formyl-1-naphthylamine;1-Naphthylformamide;Formamide, N-1-naphthalenyl-;N-(1-Naphthyl)formamide
• CAS NO: 6330-51-4
• Molecular Formula: C₁₁H₉NO
• Molecular Weight: 171.19526
• Mol File: 6330-51-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 138.0 to 142.0 °C
• Boiling Point: 386.5°C at 760 mmHg
• Flash Point: 227.8°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 3.53E-06mmHg at 25°C
• Refractive Index: 1.694
• CAS DataBase Reference: N-Formyl-1-naphthylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Formyl-1-naphthylamine(6330-51-4)
• EPA Substance Registry System: N-Formyl-1-naphthylamine(6330-51-4)

Safety Data

• Hazardous Substances Data: 6330-51-4(Hazardous Substances Data)

Usage

General Description

N-Formyl-1-naphthylamine is a chemical compound with the molecular formula C13H11NO. It is a derivative of 1-naphthylamine, which is used in the production of dyes and antioxidants. N-Formyl-1-naphthylamine itself has been used as a fluorescent probe for the detection of nitric oxide in biological systems. However, it is also classified as a suspected carcinogen and poses a risk to human health. Exposure to N-Formyl-1-naphthylamine should be minimized and appropriate safety precautions should be taken when handling this chemical.

InChI:InChI=1/C11H9NO/c13-8-12-11-7-3-5-9-4-1-2-6-10(9)11/h1-8H,(H,12,13)

Upstream product

• 66-77-3 1-naphthaldehyde 
• 64-18-6 formic acid 
• 86-57-7 1-Nitronaphthalene 
• 13504-46-6 1-naphtylaldehyde oxime 

Downstream Products

• 873414-95-0 3-phenyl-benzo[h]quinoline-4-carboxylic acid 
• 103859-95-6 N-(4-bromo-[1]naphthyl)-formamide 
• 2216-68-4 N-methylnaphthalen-1-amine 
• 233-74-9 naphtho<1,2-d>thiazole 
• 86-53-3 1-Cyanonaphthalene 
• 97766-70-6 Naphthyl-⁽¹⁾-imino-kohlensaeure-thiopentachlorphenylester-chlorid 
• 1984-04-9 1-naphthyl isonitrile 
• 313535-27-2 1-(naphthalene-1-yl)-1H-1,2,3,4-tetrazole 
• 50781-37-8 3-Phenylbenzo[h]quinoline 
• 2298-07-9 4-Bromo-1-naphthylamine 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF N-SUBSTITUTED FORMAMIDES

N-Aryl- or N-heteroarylformamides are prepared by hydrogenating a corresponding nitroarene or nitroheteroarene with formic acid and/or ammonium formate as hydrogen donor and formylating agent in the presence of at least one noble metal-based hydrogenation catalyst and a vanadium or molybdenum compound as co-catalyst.

Beckmann rearrangement of ketoximes on solid metaboric acid: A simple and effective procedure

When ketoximes admixed with solid metaboric acid (formed from boric acid at 100°C/0.1 Torr) are heated (～140°C/7-42 h), the corresponding amides or lactams are produced in excellent yields (62-92%) via the Beckmann reaction. Aromatic aldoximes undergo both dehydration to the nitrile as well as (non-stereospecific) rearrangement under the above conditions. The absence of solvent, and the mildness and low toxicity of boric acid, characterise the present procedure.