63335-24-0

Usage

Uses

Used in Pharmaceutical Industry:
Malabaricone B is used as an anti-inflammatory agent for its capacity to inhibit the production of pro-inflammatory molecules, which can be beneficial in managing inflammatory conditions.
Used in Antimicrobial Applications:
In the field of antimicrobials, Malabaricone B is utilized as an antimicrobial agent to suppress the growth of harmful bacteria, thereby contributing to the treatment and prevention of bacterial infections.
Used in Antioxidant Formulations:
Malabaricone B serves as an antioxidant in formulations designed to scavenge harmful free radicals, which can protect cells from oxidative damage and contribute to the prevention of various diseases associated with oxidative stress.
Used in Cancer Treatment:
Within oncology, Malabaricone B is considered for its potential use in the treatment of cancer due to its diverse biological activities that may help combat cancer cells and contribute to therapeutic strategies.
Used in Nutraceutical Industry:
Given its health-promoting properties, Malabaricone B can be incorporated into nutraceutical products to support general health and well-being, particularly in areas related to inflammation and oxidative stress management.

InChI:InChI=1/C21H26O4/c22-17-14-12-16(13-15-17)8-5-3-1-2-4-6-9-18(23)21-19(24)10-7-11-20(21)25/h7,10-15,22,24-25H,1-6,8-9H2

Upstream product

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• 699-83-2 2,6-dihydroxylacetophenone 
• 133839-63-1 7-(4-methoxyphenyl)-heptan-1-al 
• 133839-58-4 (Z)-1-Benzyloxy-7-(4-methoxyphenyl)hept-6-ene 
• 125732-13-0 ethyl 3-(2,6-dimethoxyphenyl)-3-oxopropanoate 
• 2040-04-2 2,6-dimethoxyacetophenone 
• 133839-68-6 1-(2-Benzyloxy-6-hydroxyphenyl)-3-hydroxy-9-(4-methoxyphenyl)nonan-1-one 
• 133839-75-5 (E)-1-(2-Benzyloxy-6-hydroxyphenyl)-9-(4-methoxyphenyl)-2-nonen-1-one 
• 133839-61-9 7-(4-methoxyphenyl)-heptan-1-ol 
• 71126-73-3 6-benzyloxyhexan-1-ol 
• 4047-24-9 1-[2-(benzyloxy)-6-hydroxyphenyl]ethanone 
• 54247-27-7 1-bromo-6-benzyloxyhexane 

Relevant academic research and scientific papers

Cytotoxic acylphenols from Myristica maingayi

From the cytotoxic AcOEt extract of the fruits of Myristica maingayi, a Myristicaceae, five new acylphenols (promalabaricones B and C, maingayic acids B and C, and maingayone) were isolated, together with the known malabaricones A-C. The structures were determined from spectral analysis, including mass spectrometry and 2D NMR. The cytotoxicity of the new compounds and that of malabaricones was assessed against KB cells. A biosynthetic pathway for malabaricones, via the corresponding promalabaricones as precursors, is suggested. (C) 2000 Elsevier Science Ltd.

Total Syntheses of Malabaricones B and C via a Cross-Metathesis Strategy

The malabaricones A-D belong to the class of diarylnonanoids isolated from the Myristicaceae family of plants. Although malabaricone C displayed various interesting biological activities, its isolation remains tedious due to its close chemical similarity to malabaricones A, B, and D. Therefore, development of an efficient synthesis route has become essential to cater to the need of large amounts of malabaricone C for its pharmacological profiling. So far there is only one report of the synthesis of malabaricone C through a lengthy sequence of reactions. We have developed an efficient and short route for the syntheses of malabaricones B and C, which will also provide a convenient access to all other members of the malabaricone family. Synthesis of an important building block, -aryl heptyl bromide, employed in the synthesis was realized by adopting a cross-metathesis reaction as the key step.