63344-48-9 Usage
Uses
Used in Organic Synthesis:
[1,1':3',1''-Terphenyl]-4'-amine is used as a key intermediate in the synthesis of complex organic molecules due to its reactive amine group and the stability provided by the terphenyl structure. It facilitates the formation of various functional groups and contributes to the development of new organic compounds with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, [1,1':3',1''-Terphenyl]-4'-amine is utilized as a starting material or a building block for the development of new drugs. Its unique structure allows for the creation of diverse molecular entities with potential therapeutic properties, including those targeting specific biological pathways or receptors.
Used in Dye Production:
[1,1':3',1''-Terphenyl]-4'-amine is employed as a precursor in the synthesis of dyes, particularly those with specific color characteristics and stability. Its chemical properties enable the production of dyes with improved performance in various applications, such as textiles, plastics, and printing inks.
Used in Chemical Product Manufacturing:
Beyond its applications in organic synthesis, pharmaceutical research, and dye production, [1,1':3',1''-Terphenyl]-4'-amine also serves as a valuable component in the manufacturing of other chemical products. Its versatility and reactivity contribute to the development of innovative materials and compounds with a wide range of applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 63344-48-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,3,4 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 63344-48:
(7*6)+(6*3)+(5*3)+(4*4)+(3*4)+(2*4)+(1*8)=119
119 % 10 = 9
So 63344-48-9 is a valid CAS Registry Number.
63344-48-9Relevant academic research and scientific papers
Direct intermolecular aniline ortho- arylation via benzyne intermediates
Truong, Thanh,Daugulis, Olafs
supporting information, p. 5964 - 5967 (2013/02/22)
A method for direct, transition-metal-free ortho-arylation of anilines by aryl chlorides, bromides, fluorides, and triflates has been developed. This methodology provides the most direct approach to 2-arylanilines since no protecting or directing groups on nitrogen are required. The arylation is functional-group tolerant, with alkene, ether, trifluoromethyl, dimethylamino, carbonyl, chloro, and cyano functionalities tolerated. Phenylation of enantiopure binaphthyldiamine affords a product with >99% ee.
Acid-Catalyzed Reactions of N-Arylhydroxylamines and Related Compounds with Benzene. Iminium-Benzenium Ions
Shudo, Koichi,Ohta, Toshiharu,Okamoto, Toshihiko
, p. 645 - 653 (2007/10/02)
N-Arylhydroxylamines react with benzene in the presence of trifluoroacetic acid (TFA) at room temperature to give diphenylamines.When TFA was replaced by a strong acid, trifluoromethanesulfonic acid (TFSA), the major products were aminobiphenyls.The nature of the reaction was explored by reactions of 4-substituted phenylhydroxylamines and dialkylaniline N-oxides with benzene.Thus, it was demonstrated that the reactive intermediates are onium-benzenium dications which are trapped by benzene to give aminobiphenyls by a mechanism similar to the Friedel-Krafts alkylation.Further evidence for the proposed reaction mechanism was the observation that nitrosobenzene and azoxybenzene reacted with benzene to give analogous products in the presence of the stronger acid.
