6337-69-5

Basic information

• Product Name: (2E)-N-hydroxy-1,1-diphenylpropan-2-imine
• CAS NO: 6337-69-5
• Molecular Formula: C₁₅H₁₅NO
• Molecular Weight: 225.2857
• Mol File: 6337-69-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 389.543°C at 760 mmHg
• Flash Point: 248.756°C
• Density: 1.033g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.558
• CAS DataBase Reference: (2E)-N-hydroxy-1,1-diphenylpropan-2-imine(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-N-hydroxy-1,1-diphenylpropan-2-imine(6337-69-5)
• EPA Substance Registry System: (2E)-N-hydroxy-1,1-diphenylpropan-2-imine(6337-69-5)

Safety Data

• Hazardous Substances Data: 6337-69-5(Hazardous Substances Data)

Usage

General Description

(2E)-N-hydroxy-1,1-diphenylpropan-2-imine is a chemical compound with the molecular formula C15H15NO. It is a hydroxylamine derivative and is commonly used as a reagent in organic synthesis. (2E)-N-hydroxy-1,1-diphenylpropan-2-imine is a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. (2E)-N-hydroxy-1,1-diphenylpropan-2-imine has also been investigated for its potential use as a radical scavenger and antioxidant. Its unique structure and reactivity make it a versatile compound with potential applications in various fields of chemistry and medicine.

Upstream product

• 67-56-1 methanol 
• 738549-82-1 2-aci-nitro-1,1-diphenyl-propane 
• 71-43-2 benzene 
• 781-35-1 1,1-diphenylacetone 
• 2042-85-5 1,2-diphenylpropan-1-one 
• 15795-69-4 β-methyl-β-nitro-α-phenylstyrene 

Downstream Products

• 1217438-25-9 1,1-diphenylpropan-2-one O-acetyl oxime 
• 1217438-38-4 1,1-diphenylpropan-2-one O-pentafluorobenzoyl oxime 
• 4757-69-1 2-methyl-3-phenyl-1H-indole 
• 65817-54-1 2,2-diphenyl-3-methyl-2H-aziridine 
• 781-35-1 1,1-diphenylacetone 

Relevant articles and documents

Modular 2,3-diaryl-2: H -azirine synthesis from ketoxime acetates via Cs2CO3-mediated cyclization

A modular 2H-azirine synthesis from ketoxime acetates via Cs2CO3-mediated cyclization has been developed. The reaction utilizes easily available starting materials and provides a general synthetic route to 2,3-diaryl-2H-azirines in good to excellent yields under mild conditions, which is complementary to the conventional approaches for the synthesis of 2H-azirines. A gram-scale reaction was performed to demonstrate the scale-up applicability of this synthetic method. Importantly, 2H-azirines can be efficiently converted to various azaheterocycles.

The Neber route to substituted indoles

Two complementary procedures have been developed for the conversion of the oximes of α-aryl ketones to azirines. On heating, the azirines rearrange smoothly to the corresponding indoles. The overall transformation offers a versatile route to indoles, complementary to the Fischer indole synthesis. Copyright

TITANIUM TRICHLORIDE MEDIATED REDUCTION OF NITROSTYRENES

Reactions of substituted nitrostyrenes with aqueous titanium trichloride afforded pyrroles, carbonyl compounds, and oximes.In some instances, divinylamines were produced as well.The reaction mechanism is rationalized taking account of electron transfer to nitroethylenes from Ti(III), followed by protonation, dimerization, cyclization, and hydrolysis.