6338-43-8

Basic information

• Product Name: 2,5-Furandicarboxylic acid, tetrahydro-
• Synonyms: 2,5-Furandicarboxylic acid, tetrahydro-;Hexaric acid, 2,5-anhydro-3,4-dideoxy-;2,5-Anhydro-3,4-dideoxyhexaric acid;NSC 40743
• CAS NO: 6338-43-8
• Molecular Formula: C₆H₈O₅
• Molecular Weight: 160.12472
• Mol File: 6338-43-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 425.5 °C at 760 mmHg
• Flash Point: 186.7 °C
• Appearance: /
• Density: 1.535 g/cm³
• Vapor Pressure: 1.97E-08mmHg at 25°C
• Refractive Index: 1.531
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Aqueous Base (Slightly), Methanol (Slightly, Heated)
• PKA: 3.04±0.40(Predicted)
• CAS DataBase Reference: 2,5-Furandicarboxylic acid, tetrahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Furandicarboxylic acid, tetrahydro-(6338-43-8)
• EPA Substance Registry System: 2,5-Furandicarboxylic acid, tetrahydro-(6338-43-8)

Safety Data

• Hazardous Substances Data: 6338-43-8(Hazardous Substances Data)

Usage

Uses

Tetrahydrofuran-2,5-dicarboxylic Acid (>80%) is used in preparation of Adipic Acid.

InChI:InChI=1/C6H8O5/c7-5(8)3-1-2-4(11-3)6(9)10/h3-4H,1-2H2,(H,7,8)(H,9,10)

Upstream product

• 104-80-3 tetrahydrofuran-2,5-dimethanol 
• 3238-40-2 furan-2,5-dicarboxylic acid 

Downstream Products

• 54885-05-1 C₈H₇F₃O₆ 
• 124-04-9 Adipic acid 
• 108-30-5 succinic acid anhydride 
• 1469368-94-2 cis-2,5-tetrahydrofurandinitrile 
• 54885-06-2 3,8-dioxabicyclo[3.2.1]octane-2,4-dione 

Relevant articles and documents

Metal-free photocatalytic aerobic oxidation of biomass-based furfural derivatives to prepare γ-butyrolactone

Efficient catalytic oxidative C-C bond cleavage with dioxygen is useful and challenging to prepare oxygenated fine chemicals from biomass. Herein, we report a catalytic strategy for the preparation of γ-butyrolactone (GBL) by photocatalytic oxidation of tetrahydrofurfuryl alcohol (THFA), tetrahydrofurfuric acid (THFCA), or other furfural derivatives at room temperature under visible-light irradiation. Metal-free mesoporous graphitic carbon nitride was used as the photocatalyst and O2was used as the oxidant. The effects of various semiconductor catalysts, light sources with different wavelengths, and the reaction time on the photocatalytic oxidation of THFA to GBL were separately investigated. Furthermore, the reaction mechanism was investigated through serious control experiments and the reaction pathway was investigated through density functional theory (DFT) calculations.

Catalytic transformation of 2,5-furandicarboxylic acid to adipic acid over niobic acid-supported Pt nanoparticles

The conversion of biomass-derived molecules into adipic acid represents a highly attractive green route for sustainable production of adipic acid, a key monomer of nylon 66 and polyurethane. Here, we report the direct synthesis of adipic acid from 2,5-furandicarboxylic acid, which can be obtained from cellulose-based 5-hydroxymethylfurfural, using a niobic acid-supported platinum catalyst under hydrogen in water.

PURIFYING CRUDE FURAN 2,5-DICARBOXYLIC ACID BY HYDROGENATION

A process for purifying a crude furan 2,5-dicarboxylic acid composition (cFDCA) by hydrogenation of a FDCA composition dissolved in a hydrogenation solvent such as water, and hydrogenating under mild conditions, such as at a temperature within a range of 130°C to 225°C by contacting the solvated FDCA composition with hydrogen in the presence of a hydrogenation catalyst under a hydrogen partial pressure within a range of 10 psi to 900 psi. A product FDCA composition is produced having a low amount of tetrahydrofuran dicarboxylic acid, a low b*, and a low amount of 5-formyl furan-2-carboxylic acid (FFCA).