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2,5-Furandicarboxylic acid
Cas No: 3238-40-2
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Furan-2,5-dicarboxylic?acid
Cas No: 3238-40-2
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Cas No: 3238-40-2
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High purity Various Specifications furan-2,5-dicarboxylic acid CAS:3238-40-2
Cas No: 3238-40-2
USD $ 100.0-500.0 / Gram 1 Gram 99999 Gram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
High quality 2,5-Furandicarboxylic Acid supplier in China
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2,5-Furandicarboxylic acid
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High Quality 99% 2,5-Furandicarboxylic acid 3238-40-2 ISO Producer
Cas No: 3238-40-2
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
2,5-Furandicarboxylic Acid
Cas No: 3238-40-2
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3238-40-2 Usage

Description

2,5-Furandicarboxylic acid (FDCA) is an organic chemical compound consisting of two carboxylic acid groups attached to a central furan ring. It was first reported as dehydromucic acid by Rudolph Fittig and Heinzelmann in 1876, who produced it via the action of concentrated hydrobromic acid upon mucic acid. It can be produced from certain carbohydrates and as such is a renewable resource, it was identified by the US Department of Energy as one of 12 priority chemicals for establishing the “green” chemistry industry of the future.Furan-2,5-dicarboxylic acid (FDCA) has been suggested as an important renewable building block because it can substitute for terephthalic acid (PTA) in the production of polyesters and other current polymers containing an aromatic moiety.wikipedia

Chemical Properties

2,5-Furandicarboxylic acid is a chemical intermediate with high sensitivity and good stability. It is soluble in water under alkaline conditions and is a white powder solid under acidic conditions, and is an important monomer for the preparation of corrosion-resistant plastics. It is irritating to eyes, respiratory tract and skin.

Uses

Different sources of media describe the Uses of 3238-40-2 differently. You can refer to the following data:
1. Interest in renewable based polymers has led to 2,5-furandicarboxylic acid being proposed as a green, sustainable alternative to the widely used petroleum-based terephthalic acid in the synthesis of polyesters. 2,5-Furandicarboxylic acid is produced from oxidation of 5-hydroxymethylfurfural (HMF) which is obtained from the dehydration of bio-based sugars such as fructose.
2. 2,5-Furandicarboxylic acid (FDCA) is a renewable, greener substitute for terephthalate in the production of polyesters. It is widely used as a precursor for the synthesis of bio-based polyesters and various other polymers.Applications of FDCA in the synthesis of several metal-organic frameworks (MOFs) have also been reported.

Preparation

2,5-Furandicarboxylic acid (FDCA) can be produced from biomass or its derived sugars or platform chemicals, and has demonstrated to be a very promising substitute for petroleum-derived polymer products.Chapter 5 - Advances in the synthesis and application of 2,5-furandicarboxylic acid

Definition

ChEBI: A member of the class of furans carrying two carboxy substituents at positions 2 and 5.

Application

2,5-Furandicarboxylic acid (FDCA) is a renewable, greener substitute for terephthalate in the production of polyesters. It is widely used as a precursor for the synthesis of bio-based polyesters and various other polymers.Applications of FDCA in the synthesis of several metal-organic frameworks (MOFs) have also been reported.

Synthesis Reference(s)

Tetrahedron Letters, 26, p. 1777, 1985 DOI: 10.1016/S0040-4039(00)98336-9

Flammability and Explosibility

Notclassified

Solubility in organics

2,5-Furandicarboxylic acid (FDCA) serves as a monomer in various polyesters and is often obtained through the oxidation of 5-hydroxymethylfurfural. In pure solvents and binary mixtures, the solubility of FDCA increased with the increasing temperature. The order from largest to smallest solubility in pure solvents was as follows: methanol, 1-butanol, isobutanol, acetic acid, water, MIBK, ethyl acetate, and acetonitrile.https://doi.org/10.1021/acs.jced.7b00927

Check Digit Verification of cas no

The CAS Registry Mumber 3238-40-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,2,3 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3238-40:
(6*3)+(5*2)+(4*3)+(3*8)+(2*4)+(1*0)=72
72 % 10 = 2
So 3238-40-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H4O5/c7-5(8)3-1-2-4(11-3)6(9)10/h1-2H,(H,7,8)(H,9,10)

3238-40-2 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Alfa Aesar (H28718)  Furan-2,5-dicarboxylic acid, 98%    3238-40-2 1g 629.0CNY Detail
Alfa Aesar (H28718)  Furan-2,5-dicarboxylic acid, 98%    3238-40-2 5g 1934.0CNY Detail
Aldrich (722081)  2,5-Furandicarboxylicacid  97% 3238-40-2 722081-5G 2,036.97CNY Detail

3238-40-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name furan-2,5-dicarboxylic acid

1.2 Other means of identification

Product number -
Other names Dehydroschleimsaeure

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3238-40-2 SDS

3238-40-2Synthetic route

5-hydroxymethyl-2-furfuraldehyde
67-47-0

5-hydroxymethyl-2-furfuraldehyde

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With Mg-Al hydrotalcite; oxygen In water at 140℃; under 750.075 Torr; for 38h; Autoclave;100%
With sodium carbonate at 80 - 120℃; under 30003 Torr; for 4h; Temperature; Reagent/catalyst;100%
With oxygen at 80℃; under 750.075 Torr; for 30h; Catalytic behavior; Time;100%
2,5-diformylfurane
823-82-5

2,5-diformylfurane

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With immobilized lipase B from Candida antarctica; dihydrogen peroxide In ethyl acetate; tert-butyl alcohol at 40℃; for 24h; Enzymatic reaction;100%
With oxygen In aq. phosphate buffer; acetonitrile at 37℃; pH=7; pH-value; Concentration; Reagent/catalyst; Temperature; Enzymatic reaction;99%
With NADH oxidase and vanillin dehydrogenase 2 co-expressed in Escherichia coli cells In aq. phosphate buffer at 30℃; for 12h; pH=7; Microbiological reaction;96%
5-Formyl-2-furancarboxylic acid
13529-17-4

5-Formyl-2-furancarboxylic acid

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With NADH oxidase and vanillin dehydrogenase 2 co-expressed in Escherichia coli cells In aq. phosphate buffer at 30℃; for 12h; pH=7; Microbiological reaction;99%
With platinum; oxygen; sodium hydrogencarbonate In water at 100℃; under 760.051 Torr; Kinetics; Reagent/catalyst;95.1%
With sodium hypochlorite In N,N-dimethyl-formamide at 25℃; for 24h; Reagent/catalyst;95%
2,5-bis-(hydroxymethyl)furan
1883-75-6

2,5-bis-(hydroxymethyl)furan

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With oxygen; sodium hydrogencarbonate In water at 90℃; for 10h; Catalytic behavior;99%
With C24H33IrN4O3; water; sodium carbonate for 18h; Reflux;88%
With recombinant 5-hydroxymethylfurfural oxidase In aq. phosphate buffer at 25℃; for 15h; pH=7; Enzymatic reaction;4.4%
2-acetyl-5-furancarboxylic acid
13341-77-0

2-acetyl-5-furancarboxylic acid

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With cesium hydroxide; sodium hypoiodite In 1,4-dioxane; water at 100℃; pH=7; Solvent; Temperature; Reagent/catalyst;99%
With oxygen; cobalt(II) acetate; manganese(II) acetate; acetic acid; sodium bromide at 240℃; for 6h; Temperature;98%
With ammonium hydroxide; iodine; potassium iodide In water; dimethyl sulfoxide at 120℃; pH=7; Reagent/catalyst; Temperature;90%
2-furanoic acid
88-14-2

2-furanoic acid

carbon dioxide
124-38-9

carbon dioxide

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With Pd/G In 1,2-dimethoxyethane at 70℃; under 7500.75 Torr; for 10h; Reagent/catalyst; Temperature; Pressure; Autoclave; Sealed tube; Green chemistry;98%
With Pd/4A molecular sieve catalyst In 1,2-dimethoxyethane at 70 - 100℃; under 75.0075 Torr; for 1.66667h; Solvent; Reagent/catalyst; Temperature; Pressure; Molecular sieve; Large scale;98.8%
Stage #1: 2-furanoic acid With potassium carbonate; caesium carbonate In water Green chemistry;
Stage #2: carbon dioxide at 260 - 285℃; under 6000.6 Torr; for 24h; Flow reactor; Green chemistry;
Stage #3: With hydrogenchloride In water pH=2; Reagent/catalyst; Pressure; Temperature; Green chemistry;
89%
furan
110-00-9

furan

carbon dioxide
124-38-9

carbon dioxide

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With Pd/G at 100℃; under 7500.75 Torr; for 10h; Reagent/catalyst; Temperature; Pressure; Autoclave; Sealed tube; Green chemistry;98.6%
With 4Å molecular sieve impregnated with palladium at 100℃; for 1.66667h; Reagent/catalyst; Temperature; Flow reactor; Large scale;98.6%
5-bromo-furan-2-carboxylic acid
585-70-6

5-bromo-furan-2-carboxylic acid

carbon monoxide
201230-82-2

carbon monoxide

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With disodium hydrogenphosphate; palladium(II) trifluoroacetate In water at 90℃; under 760.051 Torr; for 10h; Reagent/catalyst; Solvent; Temperature;97%
With potassium carbonate; triphenylphosphine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; palladium dichloride In water; N,N-dimethyl-formamide at 90℃; for 12h; Reagent/catalyst; Autoclave;91%
2-ethyl-5-methylfuran
1703-52-2

2-ethyl-5-methylfuran

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With dihydrogen peroxide In water at 60℃; for 3h; Reagent/catalyst; Temperature; Solvent;95.3%
5-chloromethylfurfural
1623-88-7

5-chloromethylfurfural

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With nickel(III) oxide; sodium hypochlorite In water at 20℃; under 760.051 Torr; for 0.5h; Reagent/catalyst;95.23%
With nitric acid In water at 80℃; for 24h;59%
Multi-step reaction with 2 steps
1: acetonitrile / 0.17 h / 20 °C
2: sodium hydrogencarbonate; oxygen; water; 10 wt% platinum on carbon / 2 h / 70 °C
View Scheme
2-furoic acid methyl ester
611-13-2

2-furoic acid methyl ester

acetic anhydride
108-24-7

acetic anhydride

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
Stage #1: 2-furoic acid methyl ester; acetic anhydride With aluminium(III) chloride hexahydrate In dichloromethane at 0 - 20℃; for 4h;
Stage #2: With sodium hypochlorite; water; sodium hydroxide at 0℃; for 2h;
95%
5-(methoxymethyl)-2-furaldehyde
1917-64-2

5-(methoxymethyl)-2-furaldehyde

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With nickel(III) oxide; sodium hypochlorite In water at 20℃; under 760.051 Torr; for 0.5h; Reagent/catalyst;94.56%
2-furoic acid methyl ester
611-13-2

2-furoic acid methyl ester

acetyl chloride
75-36-5

acetyl chloride

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
Stage #1: 2-furoic acid methyl ester; acetyl chloride With iron(III) chloride In dichloromethane at 0 - 20℃; for 4h;
Stage #2: With sodium hypochlorite; water; sodium hydroxide at 0℃; for 2h; Solvent; Reagent/catalyst;
94%
5-(1,3-dioxan-2-yl)-2-furancarboxylic acid

5-(1,3-dioxan-2-yl)-2-furancarboxylic acid

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With oxygen; sodium carbonate In water at 139.84℃; under 3750.38 Torr; for 15h; Kinetics; Autoclave;94%
5-hydroxymethyl-2-furfuraldehyde
67-47-0

5-hydroxymethyl-2-furfuraldehyde

oxygen
80937-33-3

oxygen

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With CoFe Prussian Blue Analogue film/Ni foam In water for 2.66667h; Electrochemical reaction;94%
2,5-bis-(hydroxymethyl)furan
1883-75-6

2,5-bis-(hydroxymethyl)furan

A

5-Formyl-2-furancarboxylic acid
13529-17-4

5-Formyl-2-furancarboxylic acid

B

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With oxygen; sodium hydrogencarbonate In water at 90℃; for 10h; Catalytic behavior; Reagent/catalyst;A 6%
B 93%
Multi-step reaction with 2 steps
1: recombinant 5-hydroxymethylfurfural oxidase / aq. phosphate buffer / 0.5 h / 25 °C / pH 7 / Enzymatic reaction
2: recombinant 5-hydroxymethylfurfural oxidase / aq. phosphate buffer / 1 h / 25 °C / pH 7 / Enzymatic reaction
View Scheme
Multi-step reaction with 2 steps
1: recombinant 5-hydroxymethylfurfural oxidase / aq. phosphate buffer / 0.5 h / 25 °C / pH 7 / Enzymatic reaction
2: recombinant 5-hydroxymethylfurfural oxidase / aq. phosphate buffer / 4 h / 25 °C / pH 7 / Enzymatic reaction
View Scheme
Multi-step reaction with 2 steps
1: recombinant 5-hydroxymethylfurfural oxidase / aq. phosphate buffer / 1 h / 25 °C / pH 7 / Enzymatic reaction
2: recombinant 5-hydroxymethylfurfural oxidase / aq. phosphate buffer / 1 h / 25 °C / pH 7 / Enzymatic reaction
View Scheme
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; laccase from Trametes versicolor In aq. phosphate buffer at 25℃; for 24h; pH=6;
furan-2-carboxylic acid amide
609-38-1

furan-2-carboxylic acid amide

Acetyl bromide
506-96-7

Acetyl bromide

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
Stage #1: furan-2-carboxylic acid amide; Acetyl bromide With trifluoroacetic acid In benzene at -2 - 0℃; for 8h;
Stage #2: With water; sodium methylate; chlorine at 40℃; for 3.5h;
93%
α-ketoglutarate
25466-26-6

α-ketoglutarate

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With aluminium(III) triflate; acetic acid at 120℃; under 15001.5 Torr; for 3h; Concentration;93%
5-hydroxymethyl-2-furfuraldehyde
67-47-0

5-hydroxymethyl-2-furfuraldehyde

A

5-Formyl-2-furancarboxylic acid
13529-17-4

5-Formyl-2-furancarboxylic acid

B

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With oxygen In water at 99.84℃; under 3750.38 Torr; for 12h; Reagent/catalyst;A n/a
B 92%
With 50% Fe-CeO2-500 °C; oxygen; potassium carbonate In methanol at 150℃; under 7600.51 Torr; for 10h; Temperature; Time; Reagent/catalyst; Autoclave; Overall yield = 98.2%;A 89.6%
B 5.5%
With oxygen; sodium hydrogencarbonate In water at 100℃; under 30003 Torr; for 6h; Kinetics; Reagent/catalyst; Autoclave;A 8%
B 84%
4-deoxy-5-dehydroglucaric acid dipotassium salt

4-deoxy-5-dehydroglucaric acid dipotassium salt

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With hydrogen bromide; acetic acid In water at 60℃; for 4h; Concentration; Temperature; Reagent/catalyst;91%
With hydrogen bromide; acetic acid In water at 60℃; for 4h; Reagent/catalyst; Temperature; Solvent;
With hydrogen bromide; acetic acid In water at 60℃; for 4h; Reagent/catalyst; Solvent; Temperature;
C14H20O5

C14H20O5

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With water; sodium hydroxide In methanol at 100℃; for 12h;91%
5-acetoxymethyl-2-furaldehyde
10551-58-3

5-acetoxymethyl-2-furaldehyde

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With oxygen; acetic acid; peracetic acid; manganese(II) acetate; cobalt(II) diacetate tetrahydrate at 130℃; under 7483.15 Torr; for 2h; Product distribution / selectivity; Autoclave;90.2%
With oxygen; acetic acid; peracetic acid; manganese(II) acetate; cobalt(II) diacetate tetrahydrate at 130℃; under 7483.15 Torr; for 2h; Product distribution / selectivity; Autoclave;90.2%
With manganese; oxygen; cobalt; acetic acid at 130℃; under 7483.15 Torr; Concentration;90.2%
furfural
98-01-1

furfural

carbon dioxide
124-38-9

carbon dioxide

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With oxygen at 100℃; under 6750.68 Torr; for 16h; Reagent/catalyst; Temperature; Pressure; Autoclave;90.1%
5-hydroxymethyl-2-furfuraldehyde
67-47-0

5-hydroxymethyl-2-furfuraldehyde

A

2,5-diformylfurane
823-82-5

2,5-diformylfurane

B

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With methylammonium lead bromide In acetonitrile at 15℃; for 10h; Irradiation;A 90%
B n/a
With oxygen at 110℃; for 12h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature;A 86.2%
B 11.7%
With oxygen In N,N-dimethyl-formamide at 120℃; under 750.075 Torr; for 4h; Solvent; Time; Pressure; Reagent/catalyst; Autoclave; Green chemistry;A 82.1%
B 11.5%
5-hydroxymethyl-2-furfuraldehyde
67-47-0

5-hydroxymethyl-2-furfuraldehyde

A

5-hydroxymethyl-furan-2-carboxylic acid
6338-41-6

5-hydroxymethyl-furan-2-carboxylic acid

B

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With oxygen In water at 90℃; under 750.075 Torr; for 8h; Reagent/catalyst;A 8%
B 90%
With sodium hydroxide In water at 30℃; under 7500.75 Torr; for 4h;A 89%
B 5%
With oxygen In water at 29.84℃; for 7h;A 87%
B 7%
2-dichloroacetyl-5-furancarboxylic acid

2-dichloroacetyl-5-furancarboxylic acid

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With sodium hypobromide; water; potassium carbonate In N,N-dimethyl acetamide at 140℃; pH=7;90%
furfural
98-01-1

furfural

oxalyl dichloride
79-37-8

oxalyl dichloride

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
Stage #1: furfural; oxalyl dichloride With hydrogenchloride In water; ethyl acetate at -20 - -4℃; for 10h;
Stage #2: With sodium hypochlorite; water; potassium hydrogencarbonate at 100℃; for 4h;
90%
5-bromomethyl-furan-2-carbaldehyde
39131-44-7

5-bromomethyl-furan-2-carbaldehyde

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With nickel(III) oxide; sodium hypochlorite In water at 20℃; under 760.051 Torr; for 0.5h; Reagent/catalyst;89.14%
5-(ethoxymethyl)furfural
1917-65-3

5-(ethoxymethyl)furfural

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

Conditions
ConditionsYield
With oxygen; acetic acid; peracetic acid; manganese(II) acetate; cobalt(II) diacetate tetrahydrate at 130℃; under 7483.15 Torr; for 2h; Product distribution / selectivity; Autoclave;89%
With oxygen; acetic acid; peracetic acid; manganese(II) acetate; cobalt(II) diacetate tetrahydrate at 130℃; under 7483.15 Torr; for 2h; Product distribution / selectivity; Autoclave;89%
With manganese; oxygen; cobalt; acetic acid at 130℃; under 7483.15 Torr; Temperature; Concentration;88.8%
furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

C6H8O5*2H3N

C6H8O5*2H3N

Conditions
ConditionsYield
Stage #1: furan-2,5-dicarboxylic acid With palladium on activated charcoal; hydrogen; acetic acid at 60℃; for 69h;
Stage #2: With ammonia In water at 20℃; for 0.5h;
100%
furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

1-Decanol
112-30-1

1-Decanol

didecyl 2,5-furandicarboxylate

didecyl 2,5-furandicarboxylate

Conditions
ConditionsYield
With sulfuric acid at 120℃; under 375.038 Torr; for 8h; Temperature; Reagent/catalyst;99.5%
With 1-methyl-3-(4-sulfobutyl)-1H-imidazol-3-ium hydrogensulfate at 140℃; for 10h;
methanol
67-56-1

methanol

furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

furan-2,5-dicarboxylic acid dimethyl ester
4282-32-0

furan-2,5-dicarboxylic acid dimethyl ester

Conditions
ConditionsYield
With sulfuric acid for 3h; Reflux;99%
With aluminum(III) sulphate octadecahydrate at 150℃; for 0.416667h; Sealed tube; Microwave irradiation;98.5%
With gallium(III) triflate at 175℃; for 2h; Reagent/catalyst; Sealed tube; Inert atmosphere;95%
furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

butan-1-ol
71-36-3

butan-1-ol

2,5-furandicarboxylic acid di-n-butyl ester
107821-25-0

2,5-furandicarboxylic acid di-n-butyl ester

Conditions
ConditionsYield
Silarox 30/350 at 250℃; under 7500.75 Torr; for 3h; Product distribution / selectivity;99%
silica-alumina at 250℃; under 7500.75 Torr; for 3h; Product distribution / selectivity;99%
With sulfuric acid In toluene Dean-Stark;80%
furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

furan-2,5-dicarboxylic acid dimethyl ester
4282-32-0

furan-2,5-dicarboxylic acid dimethyl ester

Conditions
ConditionsYield
With tetramethylammonium bromide; lithium carbonate In N,N-dimethyl-formamide at 150℃; for 10.5h; Temperature; Reagent/catalyst; Solvent;98.62%
With magnesium doped aluminia; tetrabutylammomium bromide In N,N-dimethyl-formamide at 150℃; for 6h; Temperature; Reagent/catalyst;66.68%
furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

furan-2,5-dicarboxylic acid dimethyl ester
4282-32-0

furan-2,5-dicarboxylic acid dimethyl ester

Conditions
ConditionsYield
In diethyl ether at -78℃;98%
furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

ethanol
64-17-5

ethanol

diethyl furan-2,5-dicarboxylate
53662-83-2

diethyl furan-2,5-dicarboxylate

Conditions
ConditionsYield
With sulfuric acid In water at 78℃; for 67h; Dean-Stark;98%
With sulfuric acid for 18h; Reflux; Inert atmosphere;98%
Silarox 30/350 at 220℃; under 11251.1 Torr; for 4h; Product distribution / selectivity;97%
furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

2,5-diformylfurane
823-82-5

2,5-diformylfurane

Conditions
ConditionsYield
With zinc(II) chloride In dichloromethane; dimethyl sulfoxide for 0.383333h;98%
furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

aluminium monohydroxide diacetate
20812-90-2, 51092-72-9, 51092-73-0

aluminium monohydroxide diacetate

C6H2O5(2-)*Al(3+)*HO(1-)

C6H2O5(2-)*Al(3+)*HO(1-)

Conditions
ConditionsYield
In water for 24h; Reflux;93%
In water at 100℃; for 96h;
furan-2,5-dicarboxylic acid
3238-40-2

furan-2,5-dicarboxylic acid

scandium (III) chloride hexahydrate

scandium (III) chloride hexahydrate

water
7732-18-5

water

2Sc(3+)*2H2O*3C6H2O5(2-)

2Sc(3+)*2H2O*3C6H2O5(2-)

Conditions
ConditionsYield
at 120℃; for 24h; Sealed tube; High pressure;93%

3238-40-2Upstream product

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