6340-82-5

Basic information

• Product Name: 2,2-dibenzyltetralin-1-one
• Synonyms: 2,2-dibenzyltetralin-1-one
• CAS NO: 6340-82-5
• Molecular Formula: C24H22O
• Molecular Weight: 326.43
• Mol File: 6340-82-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 480.8°C at 760 mmHg
• Flash Point: 209.2°C
• Appearance: /
• Density: 1.134g/cm³
• Vapor Pressure: 2.11E-09mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: 2,2-dibenzyltetralin-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dibenzyltetralin-1-one(6340-82-5)
• EPA Substance Registry System: 2,2-dibenzyltetralin-1-one(6340-82-5)

Safety Data

• Hazardous Substances Data: 6340-82-5(Hazardous Substances Data)

Usage

Chemical family

Tetralin derivatives

Physical state

White solid

Molecular weight

374.49 g/mol

Use in organic synthesis and medicinal chemistry

Building block for the synthesis of various pharmaceuticals and bioactive molecules

Biological activities

Antioxidant and anti-inflammatory properties

Potential as a scaffold

For the development of new drugs targeting various diseases

InChI:InChI=1/C24H22O/c25-23-22-14-8-7-13-21(22)15-16-24(23,17-19-9-3-1-4-10-19)18-20-11-5-2-6-12-20/h1-14H,15-18H2

Upstream product

• 100-39-0 benzyl bromide 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 132797-26-3 2-benzyl-1-tetralone 

Relevant articles and documents

N-Heterocyclic olefins as efficient phase-transfer catalysts for base-promoted alkylation reactions

N-Heterocyclic olefins (NHOs) have very recently emerged as efficient promoters for several chemical reactions due to their strong Br?nsted/Lewis basicities. Here we report the novel application of NHOs as efficient phase-transfer organocatalysts for synt

Rate enhancement with high ratio of the monoalkylated product to the dialkylated product in the alkylation of the lithium enolate of 1-tetralone with reactive alkyl halides

The reactions of the lithium enolate of 1-tetralone with reactive alkyl halides were examined in the absence and in the presence of 3 eq of various ligands for the lithium. It is shown that the rates of the reactions are enhanced greatly in the presence a tetradentate amine (1,1,4,7,10,10-hexamethyltriethylenetetramine), and the ratio of the monoalkylated product to the dialkylated product is increased under shorter reaction times.

On the π-π interaction in the benzylation of ketones

The benzylation of a set of nine ketones provides enough information to establish how the ketone structure affects the existence of a π-π interaction. The presence of a phenyl moiety starting from the a-carbon atom and flexibility in cyclic ketones are st