63402-32-4

Upstream product

• 100-16-3 4-nitrophenylhydrazone 
• 407-25-0 trifluoroacetic anhydride 
• 636-99-7 4-nitrophenylhydrazine hydrochloride 

Downstream Products

• 63402-13-1 1-Phenyl-3-{4-[N'-(2,2,2-trifluoro-acetyl)-hydrazino]-phenyl}-thiourea 
• 787-64-4 2-(4-nitrophenyl)-1-benzofurane 

Relevant academic research and scientific papers

Regioselective Decarboxylative Cycloaddition Route to Fully Substituted 3-CF3-Pyrazoles from Nitrilimines and Isoxazolidinediones

1,4-Diaryl-5-carboxamido substituted 3-trifluoromethylpyrazoles are obtained with exclusive regioselectivity under transition-metal-free conditions. This decarboxylative [3+2] cycloaddition protocol was enabled by employing trifluoromethyl nitrilimines as 1,3-dipoles, and isoxazolidinediones as CO2-masked alkynyl dipolarophiles. The applicability of this method is further manifested by its compatibility with difluoromethyl, alkyl, aryl, and heteroaryl nitrilimines, as well as the preparation of 4-carboxylic amido analogue of drug Celebrex. (Figure presented.).

Acyl hydrazino thiourea derivatives as photographic nucleating agents

Photographic nucleating agents are disclosed of the formula STR1 wherein R is a hydrogen, phenyl, alkylphenyl, cyanophenyl, halophenyl, alkoxyphenyl, alkyl, cycloalkyl, haloalkyl, alkoxyalkyl or phenylalkyl substituent; R1 is a phenylene or alkyl, halo- or alkoxy substituted phenylene group; R2 is an alkyl, haloalkyl, alkoxyalkyl or phenylalkyl substituent having up to 18 carbon atoms; a cycloalkyl substituent; phenyl or naphthyl; an alkylphenyl, cyanophenyl, halophenyl or alkoxyphenyl substituent or STR2 R3 is hydrogen, benzyl, alkoxybenzyl, halobenzyl or alkylbenzyl; THE ALKYL MOIETIES, EXCEPT AS OTHERWISE NOTED, IN EACH INSTANCE INCLUDE FROM 1 TO 6 CARBON ATOMS; AND The cycloalkyl moieties have from 3 to 10 carbon atoms.