634181-80-9

Upstream product

• 100-39-0 benzyl bromide 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 634181-78-5 (R)-4-((R)-1-(benzyloxy)-2,2-difluorobut-3-en-1-yl)-2,2-dimethyl-1,3-dioxolane 

Downstream Products

• 885621-52-3 (2S,4R,5R)-4-O-benzyl-1-O-benzoyl-3,3-difluoro-5,6-O-isopropylidenehexane-1,2,4,5,6-pentol 
• 1015418-10-6 (2S,4R,5R)-4-O-benzyl-1,2-O-bis-(tert-butyldimethylsilyl)-3,3-difluoro-5,6-O-isopropylidenehexane-1,2,4,5,6-pentol 
• 889664-08-8 (2R,4R,5R)-2-azido-4-O-benzyl-6-(tert-butyldimethylsilyloxy)-3,3-difluoro-5-(methylsulfonyloxy)hex-1-yl benzoate 
• 889664-07-7 (2R,4R,5R)-2-azido-4-O-benzyl-6-(tert-butyldimethylsilyloxy)-3,3-difluoro-5-hydroxyhex-1-yl benzoate 
• 889664-10-2 (2S,3R,5R)-5-azido-6-O-benzoyl-3-O-benzyl-4,4-difluorohexane-1,2-diyl diacetate 
• 889664-12-4 (2R,4R,5S)-2-azido-4-O-benzyl-3,3-difluoro-5-hydroxy-6-(methylsulfonyloxy)hex-1-yl benzoate 
• 889663-99-4 (2R,4R,5R)-2-azido-4-O-benzyl-3,3-difluoro-5-hydroxy-6-(methylsulfonyloxy)hex-1-yl benzoate 
• 889664-09-9 (2R,4R,5R)-2-azido-4-O-benzyl-3,3-difluoro-6-hydroxy-5-(methylsulfonyloxy)hex-1-yl benzoate 
• 889664-11-3 (2R,4R,5S)-2-azido-4-O-benzyl-3,3-difluoro-5,6-dihydroxyhex-1-yl benzoate 
• 889663-98-3 (2R,4R,5R)-2-azido-4-O-benzyl-3,3-difluoro-5,6-dihydroxyhex-1-yl benzoate 
• 889663-97-2 (2R,4R)-2-azido-4-O-benzyl-4-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-3,3-difluorobut-1-yl benzoate 
• 1015418-08-2 C₃₂H₅₀O₆F₂Si₂ 
• 1015418-11-7 (2S,4R,5R)-4-O-benzyl-1,2-O-bis-(tert-butyldimethylsilyl)-3,3-difluorohexane-1,2,4,5,6-pentol 

Relevant academic research and scientific papers

Synthesis of 3-deoxy-3,3-difluoro-d-ribohexose from gem-difluorohomoallyl alcohol

A novel synthetic route to 3-deoxy-3,3-difluoro-d-ribohexose 1 has been developed. Dihydroxidation of gem-difluorohomoallyl alcohol followed by several steps of protection and deprotection gave key intermediate 9. Oxidation of 1,5-diol 9 with 2 equiv. tri

Synthesis of L- and D-β-3′-deoxy-3′,3′- difluoronucleosides

Both L- and D-β-3′-deoxy-3′,3′-difluoronucleosides were synthesized starting from the key intermediate difluorohomoallyl alcohol 11. Deoxo-Fluor was accidentally found to be efficient in reversing the hydroxyl configuration of 34, and the desired product

3-Deoxy-3,3-difluoro-D-arabinofuranose: First Stereoselective Synthesis and Application in Preparation of gem-Difluorinated Sugar Nucleosides

The design and synthesis of gem-difluorinated sugar nucleosides were described. The key intermediate, 3-deoxy-3,3-difluoro-D-arabinofuranose 9, was first stereoselectively prepared from the chiral gem-difluorohomoallyl alcohol 12. The kinetic formation of