889663-97-2

Upstream product

• 885621-52-3 (2S,4R,5R)-4-O-benzyl-1-O-benzoyl-3,3-difluoro-5,6-O-isopropylidenehexane-1,2,4,5,6-pentol 
• 98-88-4 benzoyl chloride 
• 634181-80-9 (2R,3R,5S)-3-O-benzyl-4,4-difluoro-1,2-O-isopropylidenehexane-1,2,3,5,6-pentol 

Downstream Products

• 889664-08-8 (2R,4R,5R)-2-azido-4-O-benzyl-6-(tert-butyldimethylsilyloxy)-3,3-difluoro-5-(methylsulfonyloxy)hex-1-yl benzoate 
• 889664-07-7 (2R,4R,5R)-2-azido-4-O-benzyl-6-(tert-butyldimethylsilyloxy)-3,3-difluoro-5-hydroxyhex-1-yl benzoate 
• 889664-10-2 (2S,3R,5R)-5-azido-6-O-benzoyl-3-O-benzyl-4,4-difluorohexane-1,2-diyl diacetate 
• 889664-12-4 (2R,4R,5S)-2-azido-4-O-benzyl-3,3-difluoro-5-hydroxy-6-(methylsulfonyloxy)hex-1-yl benzoate 
• 889663-99-4 (2R,4R,5R)-2-azido-4-O-benzyl-3,3-difluoro-5-hydroxy-6-(methylsulfonyloxy)hex-1-yl benzoate 
• 889664-09-9 (2R,4R,5R)-2-azido-4-O-benzyl-3,3-difluoro-6-hydroxy-5-(methylsulfonyloxy)hex-1-yl benzoate 
• 889664-11-3 (2R,4R,5S)-2-azido-4-O-benzyl-3,3-difluoro-5,6-dihydroxyhex-1-yl benzoate 
• 889663-98-3 (2R,4R,5R)-2-azido-4-O-benzyl-3,3-difluoro-5,6-dihydroxyhex-1-yl benzoate 

Relevant academic research and scientific papers

Synthesis and biological evaluation of glycosidase inhibitors: gem-difluoromethylenated nojirimycin analogues

In our ongoing program aimed at the design, synthesis, and biological evaluation of novel gem-difluoromethylenated glycosidase inhibitors, gem-4,4-difluoromethylenated iminosugars (5-9) were synthesized. The biological evaluation of these synthetic iminos