63427-91-8 Usage
General Description
1-benzyl 2-Methyl pyrrolidine-1,2-dicarboxylate, also known as bupropion, is a medication used primarily as an antidepressant and smoking cessation aid. It is a chemical compound that works by inhibiting the reuptake of certain neurotransmitters in the brain, namely dopamine and norepinephrine. This action helps to restore the balance of these neurotransmitters in the brain, leading to improvements in mood and a reduction in cravings for nicotine. Bupropion is also sometimes prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and as an aid to help people quit smoking. It is available in various formulations, including immediate-release and extended-release tablets, and is typically taken orally. As with any medication, bupropion can cause side effects, and it should only be used under the guidance of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 63427-91-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,4,2 and 7 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 63427-91:
(7*6)+(6*3)+(5*4)+(4*2)+(3*7)+(2*9)+(1*1)=128
128 % 10 = 8
So 63427-91-8 is a valid CAS Registry Number.
63427-91-8Relevant articles and documents
Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor
Krainz, Tanja,Lamade, Andrew M.,Du, Lina,Maskrey, Taber S.,Calderon, Michael J.,Watkins, Simon C.,Epperly, Michael W.,Greenberger, Joel S.,Baylr, Hülya,Wipf, Peter,Clark, Robert S. B.
, p. 2868 - 2879 (2018/09/25)
The poly(ADP-ribose) polymerase (PARP) family of enzymes plays a crucial role in cellular and molecular processes including DNA damage detection and repair and transcription; indeed, PARP inhibitors are under clinical evaluation as chemotherapeutic adjunc
1H-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent PARP inhibitors
-
Page/Page column 14, (2008/06/13)
Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of For
