141870-95-3Relevant articles and documents
Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor
Krainz, Tanja,Lamade, Andrew M.,Du, Lina,Maskrey, Taber S.,Calderon, Michael J.,Watkins, Simon C.,Epperly, Michael W.,Greenberger, Joel S.,Baylr, Hülya,Wipf, Peter,Clark, Robert S. B.
, p. 2868 - 2879 (2018)
The poly(ADP-ribose) polymerase (PARP) family of enzymes plays a crucial role in cellular and molecular processes including DNA damage detection and repair and transcription; indeed, PARP inhibitors are under clinical evaluation as chemotherapeutic adjunc
SATURATED FUSED [1,2-B] PYRIDAZINONE COMPOUNDS
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Page/Page column 62-63, (2008/12/06)
The invention is directed to saturated fused [1,2-b]pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
Preparation, Isolation and X-Ray Crystallographic Structure Determination of a Stable, Crystalline Carbonic Anhydride of an N-Protected α-Amino Acid
Chan, Chat-On,Cooksey, Christopher J.,Crich, David
, p. 777 - 780 (2007/10/02)
The reaction of methyl (2S,3aR,8aS)-2-carboxy-8-phenylsulfonyl-1,2,3,3a,8,8a-hexahydropyrrolo-indole-1-carboxylate and isobutyl chloroformate in tetrahydrofuran at -15 deg C in the presence of trimethylamine results in the formation of the correspo