63438-08-4

Basic information

• Product Name: 1-(4-Bromobutoxy)-2-benzylbenzene
• Synonyms: 1-(4-Bromobutoxy)-2-benzylbenzene
• CAS NO: 63438-08-4
• Molecular Formula: C₁₇H₁₉BrO
• Molecular Weight: 319.24
• Mol File: 63438-08-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-Bromobutoxy)-2-benzylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Bromobutoxy)-2-benzylbenzene(63438-08-4)
• EPA Substance Registry System: 1-(4-Bromobutoxy)-2-benzylbenzene(63438-08-4)

Safety Data

• Hazardous Substances Data: 63438-08-4(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 1333434-76-6 2-bromophenyl tert-butyl carbonate 
• 110-52-1 1,4-dibromo-butane 
• 28994-41-4 o-Benzylphenol 

Downstream Products

• 13259-73-9 2-(4-dimethylaminobutoxy) diphenyl methane hydrochloride 
• 90293-01-9 bifemelane 

Relevant articles and documents

Nickel-Catalyzed Electrochemical C(sp3)?C(sp2) Cross-Coupling Reactions of Benzyl Trifluoroborate and Organic Halides**

Reported here is the redox neutral electrochemical C(sp2)?C(sp3) cross-coupling reaction of bench-stable aryl halides or β-bromostyrene (electrophiles) and benzylic trifluoroborates (nucleophiles) using nonprecious, bench-stable NiCl2?glyme/polypyridine catalysts in an undivided cell configuration under ambient conditions. The broad reaction scope and good yields of the Ni-catalyzed electrochemical coupling reactions were confirmed by 50 examples of aryl/β-styrenyl chloride/bromide and benzylic trifluoroborates. Potential applications were demonstrated by electrosynthesis and late-stage functionalization of pharmaceuticals and natural amino acid modification, and three reactions were run on gram-scale in a flow-cell electrolyzer. The electrochemical C?C cross-coupling reactions proceed through an unconventional radical transmetalation mechanism. This method is highly productive and expected to find wide-spread applications in organic synthesis.