634611-89-5

Upstream product

• 98-88-4 benzoyl chloride 
• 634611-82-8 (Z)-(S)-6,7-Dimethyl-3-trimethylsilanylmethyl-octa-2,7-dien-1-ol 
• 93748-48-2 (S)-3-hydroxy-2,3-dimethylbutyl 4-methylbenzenesulfonate 
• 634611-77-1 (R)-4-Iodo-2,3-dimethyl-but-1-ene 
• 1026254-76-1 (Z)-(S)-3-(Diethoxy-phosphoryloxy)-6,7-dimethyl-octa-2,7-dienoic acid methyl ester 
• 634611-75-9 (Z)-(S)-6,7-Dimethyl-3-trimethylsilanylmethyl-octa-2,7-dienoic acid methyl ester 
• 634611-78-2 (S)-6,7-Dimethyl-3-oxo-oct-7-enoic acid methyl ester 
• 112763-33-4 (3R)-2,3-dimethyl-4-(p-tolylsulfonyloxy)but-1-ene 
• 73295-12-2 (S)-2,3-dimethyl-1,3-butanediol 

Relevant academic research and scientific papers

Electrophilic Cyclization of 1,6-Dienes Containing an Allylsilane Moiety - Enantioselective Synthesis of cis- and trans-γ-Irone

In this paper, we report the first examples of Lewis acid and mercuric trifluoroacetate promoted cyclizations of 1,6-dienes containing an allylsilane moiety. Mercuric trifluoroacetate has been proved to be the reagent of choice leading to methylenecyclohexane derivatives in good yields and with complete regioselectivity albeit with poor diastereoselectivity. Using this methodology a stereodivergent synthesis of enantiomerically pure (-)-(2S,6R)-cis-γ -irone and (-)-(2S,6S)-trans-γ-irone, two precious aroma constituents, has been accomplished. This represents an innovative approach with respect to previous syntheses of γ-irones. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.