63472-03-7

Basic information

• Product Name: 4-(biphenyl-4-yl)-4-oxo-2-phenylbutanenitrile
• CAS NO: 63472-03-7
• Molecular Formula: C₂₂H₁₇NO
• Molecular Weight: 311.3765
• Mol File: 63472-03-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 526°C at 760 mmHg
• Flash Point: 271.9°C
• Density: 1.136g/cm³
• Vapor Pressure: 3.73E-11mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: 4-(biphenyl-4-yl)-4-oxo-2-phenylbutanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(biphenyl-4-yl)-4-oxo-2-phenylbutanenitrile(63472-03-7)
• EPA Substance Registry System: 4-(biphenyl-4-yl)-4-oxo-2-phenylbutanenitrile(63472-03-7)

Safety Data

• Hazardous Substances Data: 63472-03-7(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 2453-44-3 3-Phenyl-2-propen-1-one 
• 151-50-8 potassium cyanide 

Downstream Products

• 39206-66-1 γ-Oxo-α-Phenyl-4-biphenylbuttersaeure 
• 5333-39-1 4-biphenyl-4-yl-4-oxo-2-phenyl-butyric acid methyl ester 

Relevant articles and documents

Thiourea-functionalized magnetic hydroxyapatite as a recyclable inorganic-organic hybrid nanocatalyst for conjugate hydrocyanation of chalcones with TMSCN

The recoverable nanomagnetic catalyst was manufactured based on thiourea modified magnetic hydroxyapatite. Magnetic hydroxyapatite (mHAp) as the inorganic-organic hybrid support was fabricated using co-precipitate condition and then modified via the covalently anchoring of 1-(3,5-bis(trifluoromethyl)phenyl-3-propyl)thiourea. The hybrid nano-catalyst has been identified by TEM, SEM, FTIR, BET, TGA, and XRD. This nanocatalyst appeared efficient and robust in the 1,4-addition reaction of TMSCN to α,β-unsaturated aromatic enones in excellent yields (85-96%) under mild reaction condition and simple work-up process. This recoverable organocatalyst has a great potential as an industrially viable and eco-safe catalyst.