63473-46-1

Basic information

• Product Name: L-Phenylalanine, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-methionyl]-, methyl ester
• CAS NO: 63473-46-1
• Molecular Formula: C20H30N2O5S
• Molecular Weight: 410.535
• Mol File: 63473-46-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-methionyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-methionyl]-, methyl ester(63473-46-1)
• EPA Substance Registry System: L-Phenylalanine, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-methionyl]-, methyl ester(63473-46-1)

Safety Data

• Hazardous Substances Data: 63473-46-1(Hazardous Substances Data)

Upstream product

• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 22823-50-3 tert-butyloxycarbonylmethionine dicyclohexylammonium salt 
• 2488-15-5 N-tert-butoxycarbonyl-L-methionine 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 

Downstream Products

• 132718-61-7 N^α-tert-butoxycarbonylisoleucyl-histydyl-<2-(3-aminopyrrolidin-2-on-1-yl)-3-phenylpropanoic acid> p-nitrobenzylester 
• 132718-64-0 2-(3-tert-butoxycarbonylamino-pyrrolidin-2-on-1-yl)-3-phenylpropanoic acid p-nitrobenzylester 
• 79839-24-0 Boc-Met-Phe methyl ester methylsulfonium iodide 
• 79839-27-3 2-(3-tert-butoxycarbonylaminopyrrolidin-2-on-1-yl)-3-phenylpropanoic acid 

Relevant articles and documents

Pd-Catalyzed Site-Selective C(sp2)-H Olefination and Alkynylation of Phenylalanine Residues in Peptides

Pd-catalyzed site-selective C(sp2)-H olefination and alkynylation of phenylalanine residues in peptides are described. The amino acids within the peptides are used as native bidentate directing groups to facilitate C-H functionalization. This p

9-Silafluorenyl Dichlorides as Chemically Ligating Coupling Agents and Their Application in Peptide Synthesis

A fundamentally simple, mild, and practical procedure for peptide bond formation is reported that employs a stoichiometric amount of easy-to-access 9-silafluorenyl dichlorides as the coupling agent. Without initial preactivation or elaboration of the carboxylic acid or amine termini of the amino acids, the developed reagent is proposed to act through an unprecedented chemical ligation mechanism, bringing the two coupling partners together before being subsequently eliminated. The desired amides or peptide bonds are thus furnished in good yields and with low to no epimerization.

Dipeptidyl nitriles as human dipeptidyl peptidase I inhibitors

Using a dipeptide nitrile scaffold we have identified a potent and selective inhibitor of human dipeptidyl peptidase I.