63549-35-9 Usage
General Description
(E)-1-(7-methyl-2,3-dihydro-1H-inden-4-yl)-1-(naphthalen-1-yl)methanimine hydrochloride (1:1) is a chemical compound that consists of a hydrochloride salt of the imine form of a naphthalene derivative. Its molecular structure includes a double bond and a methyl group attached to the indene ring, as well as a naphthalene moiety. (E)-1-(7-methyl-2,3-dihydro-1H-inden-4-yl)-1-(naphthalen-1-yl)methanimine hydrochloride (1:1) may have potential applications in pharmaceutical or research settings due to its unique structure and potential biological activity. Additionally, as a salt, the hydrochloride form of this compound may be more stable and have improved solubility compared to the free base form, making it more suitable for certain applications.
Check Digit Verification of cas no
The CAS Registry Mumber 63549-35-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,5,4 and 9 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 63549-35:
(7*6)+(6*3)+(5*5)+(4*4)+(3*9)+(2*3)+(1*5)=139
139 % 10 = 9
So 63549-35-9 is a valid CAS Registry Number.
63549-35-9Relevant articles and documents
Improved Synthesis of 3-Methylcholanthrene
Tang, Ping Wah,Maggiulli, Cataldo A.
, p. 3429 - 3432 (2007/10/02)
An improved synthesis of 7-methylindan-4-yl 1-naphthyl ketone (3), an important precursor of 3-methylcholanthrene (1), has been developed.The key intermediates for 3, 4-cyano-7-methylindan (2a) and 4-(ethoxycarbonyl)-7-methylindan (2b), were conveniently prepared in high yields by reaction of 1-(1-pyrrolidino)cyclopentene (6) with sorbonitrile (5a) or ethyl sorbate (5b), followed by aromatization with sulfur. 1-Naphthylmagnesium bromide (4b) in the presence of cuprous iodide reacted cleanly with 4-(chloromethanoyl)-7-methylindan (12) to give 3.The Friedel-Crafts acylation of naphthalene with 12 afforded 84percent of 3 and 16percent of β isomer 13.Alternatively, 3 was prepared in 75percent yield by condensation of Grignard reagent 4b with 2a in THF.Thermal annelation of 3 afforded 1 in 41.5percent yield.
