63571-96-0

Basic information

• Product Name: Benzeneethanethioic acid, a-oxo-, S-ethyl ester
• CAS NO: 63571-96-0
• Molecular Formula: C10H10O2S
• Molecular Weight: 194.254
• Mol File: 63571-96-0.mol

Chemical Properties

• CAS DataBase Reference: Benzeneethanethioic acid, a-oxo-, S-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanethioic acid, a-oxo-, S-ethyl ester(63571-96-0)
• EPA Substance Registry System: Benzeneethanethioic acid, a-oxo-, S-ethyl ester(63571-96-0)

Safety Data

• Hazardous Substances Data: 63571-96-0(Hazardous Substances Data)

Upstream product

• 84543-51-1 2,2,2-Tris-ethylsulfanyl-1-phenyl-ethanone 
• 74-96-4 ethyl bromide 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 25726-04-9 phenylglyoxylyl chloride 
• 75-08-1 ethanethiol 
• 611-73-4 Benzoylformic acid 
• 93-58-3 benzoic acid methyl ester 
• 82027-28-9 S-ethyl 2-hydroxy-2-phenylethanethioate 

Downstream Products

• 82027-28-9 S-ethyl 2-hydroxy-2-phenylethanethioate 
• 71910-56-0 N-methyl-2-oxo-N,2-diphenylacetamide 
• 22711-21-3 4-methoxybenzil 
• 40103-80-8 1-(3-methoxyphenyl)-2-phenylethane-1,2-dione 
• 58022-58-5 1-(4-methylsulfanylphenyl)-2-phenyl-1,2-ethanedione 
• 86358-27-2 1-(benzo[d][1,3]dioxol-5-yl)-2-phenylethane-1,2-dione 
• 16216-14-1 o-methylbenzil 
• 134-81-6 benzil 
• 16216-09-4 2-(1-naphthyl)-1-phenylethanedione 
• 65648-94-4 1-(naphthalen-2-yl)-2-phenylethane-1,2-dione 

Relevant articles and documents

Umpolung Reaction of α-Imino Thioesters and the Subsequent C-C Bond Formation with the Unexpected Alkylthio Rearrangement

An umpolung reaction of the α-imino thioester was examined, and we found that α-imino thioesters were more effective substrates for the umpolung N-alkylation than conventional α-imino esters and they gave N-alkylated amino thioesters in high yields under mild reaction conditions in a short time. A new type of C-C bond formation followed by an unexpected rearrangement of the alkylthio group took place with the unsaturated ketones to afford the β-alkylthio-α-amino thioesters in high yields with good diastereoselectivity.

1,2-dicarbonyl compounds and synthesis method thereof

The invention discloses a synthesis method of new 1,2-dicarbonyl compounds. The 1,2-dicarbonyl compounds are represented by a formula (1), and the synthesis method comprises the steps: adopting alpha-hydroxyketone, a sulfur reagent and alkyl bromide as re

Asymmetrie aerobic oxidation of α-hydroxy acid derivatives by C 4-symmetric, vanadate-centered, tetrakisvanadyl(V) clusters derived from N-salicylidene-α-aminocarboxylates

(Chemical Equation Presented) A series of chiral vanadyl(V) methoxides bearing 3-t-butyl-5-substituted N-salicylene-L-valinate and L-t-leucinate as chiral auxiliaries has been prepared. In all cases except the 3,5-di-t-butyl analogue, they exist as monomers both in solution and in the single crystal state. In the case of the 3,5-di-t-butyl analogue, the architectural nature of the vanadyl(V) complex highly depends on the base used during the complex formation event. A pentanuclear C4-symmetric complex was formed when potassium salts were employed instead of the corresponding sodium salts. A central vanadate(V) unit serves to grip four identical chiral monomelic vanadyl(V) units together, by which a potassium ion sits on top of the four flanking units through carbonyl coordinations and serves to hold the whole cluster by cooperation with the central vanadate(V) unit. In comparison with the corresponding monomelic vanadyl(V) methoxide complex, the cluster complex was utilized to facilitate the asymmetric aerobic oxidations of various racemic α-hydroxyesters, -amides, and -thioesters with excellent selectivity factors (krel 40 to >500).

Isomerization of Trimethyl α-Keto Trithioorthocarboxylates into α,α-Bis(methylthio) Thiolcarboxylates. A New Rearrangement of Synthetic Interest

A study was made of the isomerization reaction of a great variety of trimethyl α-keto trithioorthocarboxylates to α,α-bis(methylthio) thiolcarboxylates, intermediates of high synthetic value for the synthesis of α-arylpropionic acids. The reaction was carried out in methylene chloride in the presence of catalytic amounts of trityl perchlorate or methanesulfonic acid and was complete in 2 h at rt. In most of the investigated cases the result was positive, the yields usually being greater than 90%. Also the reaction mechanism was subjected to an experimental study.

Photochemical Reactions of Mercapto/Amino Substituted Alkyl Phenylglyoxylates Induced by Intramolecular Electron Transfer

2'-Alyothio ethyl phenylglyoxylates (1) and 2'-dimethylamino ethyl phenylglyoxylate (10) were synthesized and their photochemistry studied.In contrast to their oxygen analog 3, which give normal Norrish type II cleavage products, the title compounds undergo intermolecular electron transfer from the heteroatom (sulfur/nitrogen) to the excited carbonyl group, followed by proton transfer and subsequent closing of the resulting biradical to produce seven-mebered (11) lactones in high yield.Thiadialkyl phenylglyoxylates (9) react inefficiently due to intramolecular self-quenching of phenylgluoxylate chromophores.The photoreactivity of α-oxothioester (14) was compared with that of its nitrogen (α-oxoamide) and oxygen (phenylglyoxylate) counterparts. - Keywords: Photochemical; Mercapto; Amino; Phenylglyoxylates; Electron Transfer