63619-51-2

Basic information

• Product Name: 4-bromo-4'-(pentyloxy)-1,1'-biphenyl
• Synonyms: 4-bromo-4'-(pentyloxy)-1,1'-biphenyl;4-Bromo-4'-(pentyloxy)biphenyl;4-(4-n-Pentyloxyphenyl)-bromobenzene
• CAS NO: 63619-51-2
• Molecular Formula: C₁₇H₁₉BrO
• Molecular Weight: 319.23616
• Mol File: 63619-51-2.mol
• Article Data: 18

Chemical Properties

• Melting Point: 132 °C(Solv: hexane (110-54-3))
• Boiling Point: 401.6±28.0 °C(Predicted)
• Appearance: /
• Density: 1.223±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-bromo-4'-(pentyloxy)-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-4'-(pentyloxy)-1,1'-biphenyl(63619-51-2)
• EPA Substance Registry System: 4-bromo-4'-(pentyloxy)-1,1'-biphenyl(63619-51-2)

Safety Data

• Hazardous Substances Data: 63619-51-2(Hazardous Substances Data)

Upstream product

• 628-17-1 amyl iodide 
• 29558-77-8 4-bromo-4'-hydroxybiphenyl 
• 78-93-3 butanone 
• 110-53-2 1-Bromopentane 

Downstream Products

• 158938-08-0 4′′-(pentyloxy)-1,1′:4′,1′′-terphenyl-4-carboxylic acid 
• 158937-65-6 2,4,5-trichlorophenyl 4-(4'-pentyloxybiphenyl)benzoate 
• 166663-25-8 Anidulafungin 
• 158937-25-8 4-(4-n-pentyloxyphenyl)phenylboronic acid 
• 158937-30-5 4′′-pentyloxy-[1,1':4',1′′-terphenyl]-4-carboxylic acid methyl ester 
• 1334511-82-8 C₄₅H₆₀N₄O₈ 
• 1203557-57-6 C₄₄H₅₈N₄O₉ 
• 59748-15-1 4'-n-pentyloxybiphenyl-4-carboxylic acid 
• 52364-71-3 4'-(pentyloxy)-4-biphenylcarbonitrile 

Relevant articles and documents

Novel echinocandin antifungals. Part 1: Novel side-chain analogs of the natural product FR901379

A series of novel acylated analogs of the novel water-soluble echinocandin FR901379 have been prepared and evaluated for antifungal and hemolytic activity. A relationship between antifungal activity and lipophilicity of the acyl side chain, expressed as Clog P was demonstrated, and an analog (3c) with 5.5- to 8-fold superior in vivo activity relative to the previously disclosed 4-(n-octyloxy)benzoyl side chain analog, FR131535 obtained.

Anidulafungin side chain intermediate 4''-(pentyloxy)-[1,1':4',1''-terphenyl]-4-carboxylic acid

The invention relates to the preparation method of anidulafungin side chain intermediate 4''-(pentyloxy)-[1,1':4',1''-terphenyl]-4-carboxylic acid. The preparation method includes the steps of S1, subjecting 4 hydroxy-4'-bromobiphenyl and 1-bromopentane to nucleophilic substitution to obtain 4'-bromo-4-n-amyloxybiphenyl; S2, subjecting the 4'-bromo-4-n-amyloxybiphenyl and tetrahydroxydiboron to Suzuki coupling reaction to obtain 4-pentyloxy-4'-biphenylboronic acid; S3, subjecting the 4-pentyloxy-4'-biphenylboronic acid and methyl 4-iodobenzoate to Suzuki coupling reaction to obtain methyl 4''-(pentyloxy)-[1,1',4'-1''-terphenyl]-4-formate; S4, hydrolyzing to obtain 4''-(pentyloxy)-[1,1':4',1''-terphenyl]-4-carboxylic acid. arylboronic acid is prepared through Suzuki coupling; the target product is then prepared through Suzuki coupling and alkali hydrolysis; the preparation method has the advantages of low cost and good process operation simplicity and safety.

Synthesis of liquid crystal molecules based on bis(biphenyl)diacetylene and their liquid crystallinity

We synthesized novel liquid crystalline molecules that contain a bis(biphenyl)diacetylene mesogen and confirmed their structures by 1HNMR, 13CNMR, and FT-IR spectroscopy and mass spectrometry. These compounds formed thermotropic liquid crystals in a wide temperature region that was well characterized by optical microscopic and X-ray measurements.