628-17-1Relevant articles and documents
A mild and highly chemoselective iodination of alcohol using polymer supported DMAP
Das, Diparjun,H Anal, Jasha Momo,Rokhum, Lalthazuala
, p. 1695 - 1701 (2017/03/08)
The synthesis of organic compounds using polymer supported catalysts and reagents, where the required product is always in solution, has been of great interest in recent years, both in industries and academia especially in pharmaceutical research. Here, a simple and efficient method for conversion of alcohols into their iodides in high yield using polymer supported 4-(Dimethylamino)pyridine (DMAP) is described. Polymer supported DMAP is used in catalytic amount and is recovered and reused several times. Additionally, this method is highly chemoselective. [Figure not available: see fulltext.]
Simple synthesis of fresh alkyl iodides using alcohols and hydriodic acid
Klein, Suzane M.,Zhang, Cungen,Jiang, Yu Lin
, p. 2638 - 2641 (2008/09/19)
A simple synthesis of fresh alkyl iodides using alcohols and hydriodic acid (HI) is reported. The alkyl iodides were obtained in quick and easy work-up with good to excellent yields (66-94%) and very high purities (97-99%). Freshly prepared iodomethane and 1-iodobutane were applied to synthesize biologically relevant 3,7-dimethyladenine and 9-butyladenine, which were characterized thoroughly using 1D and 2D NMR, individually.
Direct bromination and iodination of non-activated alkanes by hypohalite reagents
Montoro, Raul,Wirth, Thomas
, p. 1473 - 1478 (2007/10/03)
The direct functionalisation of alkanes through bromination and iodination has been successfully achieved. The combination of stoichiometric mixtures of elemental halogen and sodium alkoxides leads to the formation of alkyl hypobromites and hypoiodites as reagents. The halogenation occurs without external photostimulation under thermal reaction conditions. Georg Thieme Verlag Stuttgart.
