63649-13-8Relevant academic research and scientific papers
Novel Hybrid Molecules of Epinastine and Mefenamic Acid for Bioactive Assessment as Potential Anti-inflammatory Agents
Lee, Ju Mi,Damodar, Kongara,Lee, Yeontaek,Woo, Hyeong Ryeol,Suh, Hong Won,Jeon, Sung Ho,Lee, Jeong Tae
, p. 444 - 449 (2020/03/04)
A set of novel epinastine (1) and mefenamic acid (2) hybrids (3–7) tethered via amide bond were designed and synthesized with the artistry of molecular hybridization. Then their inhibitory effect on nitric oxide (NO) production in LPS-induced RAW-264.7 ma
Depsipeptides containing non-natural amino acids
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, (2008/06/13)
A depsipeptide containing a non-natural amino acid(s) having the formula (1) wherein R1represents a C5-C20alkyl group and others; R2represents —O—CO—CH(R5)—X—CH(R6)—NH— (wherein X represent
95. Design and Synthesis of Potent Macrocyclic Benzolactam Growth Hormone Secretagogues
DeVita, Robert J.,Frontier, Alison J.,Schoen, William R.,Wyvratt, Matthew J.,Fisher, Michael H.,Cheng, Kang,Chan, Wanda W.-S.,Butler, Bridget S.,Smith, Roy G.
, p. 1244 - 1259 (2007/10/03)
The synthesis of a variety of potent macrocyclic growth hormone secretagogues, i.e. 5, 9, 12, and 20-22, based on the known lead structure L-692,429 (1) is described. These conformationally constrained growth hormone secretagogues were prepared by joining
