636581-82-3

Upstream product

• 636581-81-2 3,5-bis-O-(2,4-dichlorobenzyl)-1-O-methyl-α-D-ribofuranose 

Downstream Products

• 677299-15-9 3,5-bis-O-(2,4-dichlorophenylmethyl)-1-O-methyl-2-C-methyl-D-ribofuranose 
• 1044589-93-6 (3R,4R,5R)-5-(2,4-dichlorobenzyloxymethyl)-4-(2,4-dichlorobenzyloxy)-3-ethynyl-2-methoxy-tetrahydrofuran-3-ol 
• 636581-83-4 3,5-bis-O-(2,4-dichlorobenzyl)-2-C-vinyl-1-O-methyl-α-D-ribofuranose 
• 1044589-94-7 (2R,3R,4R,5R)-2-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-4-((2,4-dichlorobenzyl)oxy)-5-(((2,4-dichlorobenzyl)oxy)methyl)-3-ethynyltetrahydrofuran-3-ol 
• 1044589-82-3 (2R,3R,4R,5R)-2-(4-amino-pyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-hydroxymethyl-tetrahydro-furan-3,4-diol 

Relevant academic research and scientific papers

NEW ANTIVIRAL MODIFIED NUCLEOSIDES

This invention relates to novel compounds that have various medicinal applications, e.g. for the treatment and/or prevention of viral infections. wherein: X is CH or CR6; R1 is halogen, NR7R8 or OR9; R2 is H, halogen, or NR7R8; R3 is H, alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocycloalkyl or heteroaryl, each of which is optionally substituted with one or more substituents; R4 is H, acyl or an amino acid ester; R5 is H, acyl or an amino acid ester; R6 is alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocycloalkyl, heteroaryl, halogen, cyano, nitro, hydroxy, alkoxy, alkylthio, amino, alkylamino, carboxy, carboxamide or alkyloxycarbonyl, each of which is optionally substituted with one or more substituents; R7 and R8 are independently selected from the group consisting of H, alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocycloalkyl, heteroaryl, amino, alkylamino, arylamino, hydroxy, alkoxy, arylcarbonyl and alkylcarbonyl, each of which is optionally substituted with one or more substituents; and R3 is H, alkyl, alkenyl, alkynyl, aryl, cycloalkyl, heterocycloalkyl, heteroaryl, alkylcarbonyl or arylcarbonyl, each of which is optionally substituted with one or more substituents;

NEW ANTIVIRAL MODIFIED NUCLEOSIDES

This invention relates to novel compounds that have various medicinal applications, e.g. for the treatment and/or prevention of viral infections.

NOVEL NUCLEOSIDE ANALOGS FOR TREATMENT OF VIRAL INFECTIONS

This invention relates to novel nucleoside compounds of formula (I) that have various medicinal applications, e.g. for the treatment and/or prevention of viral infections.

5-nitro-nucleoside compounds for treating viral infections

Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.

NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE

The present invention provides nucleoside compounds and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-d