6366-77-4

Basic information

• Product Name: Ala-Lys-OH
• Synonyms: Ala-Lys-OH;L-Ala-L-Lys-OH;N2-L-Alanyl-L-lysine;Nα-L-Alanyl-L-lysine
• CAS NO: 6366-77-4
• Molecular Formula: C₉H₁₉N₃O₃
• Molecular Weight: 217.27
• Mol File: 6366-77-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ala-Lys-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Ala-Lys-OH(6366-77-4)
• EPA Substance Registry System: Ala-Lys-OH(6366-77-4)

Safety Data

• Hazardous Substances Data: 6366-77-4(Hazardous Substances Data)

Downstream Products

• 56-41-7 L-alanin 
• 56-87-1 L-lysine 
• 5910-89-4 2,3-dimethylpyrazine 
• 13360-65-1 2-ethyl-3,6-dimethylpyrazine 
• 54410-83-2 2,3-dimethyl-5-(2-methylpropyl)pyrazine 
• 55138-77-7 2,5-dimethyl-3-(E-1-propenyl)pyrazine 
• 80935-98-4 3-ethenyl-2,5-dimethylpyrazine 
• 22047-26-3 1-(6-methyl-2-pyrazinyl)-1-ethanone 
• 22047-27-4 1-(5-methylpyrazin-2-yl)ethanone 
• 13360-64-0 2-ethyl-5-methypyrazine 
• 15707-34-3 5-ethyl-2,3-dimethylpyrazine 
• 290-37-9 1,4-pyrazine 
• 13238-84-1 2,5-diethylpyrazine 
• 13925-03-6 2-ethyl-6-methylpyrazine 

Relevant articles and documents

Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture

Photoaffinity labeling (PAL) is one of the upcoming and powerful tools in the field of molecular recognition. It includes the determination of dynamic parameters, such as the identification and localization of the target protein and the site of drug binding. In this study, a photoaffinity-labeled probe for full-length human immunodeficiency virus-1 integrase (HIV-1 IN) capture was designed and synthesized, following the structure of the FDA-approved drug Raltegravir. This photoprobe was found to retain the HIV IN inhibitory potential in comparison with its parent molecule and demonstrates the ability to label the HIV-1 IN protein. Putative photoprobe/inhibitor binding sites near the catalytic site were then identified after protein digestion coupled to mass and molecular modeling analyses.