13238-84-1Relevant articles and documents
Thermal characterization of the solid state and raw material fluconazole by thermal analysis and pyrolysis coupled to GC/MS
Moura, Elisana Afonso,Correia, Lidiane Pinto,Pinto, Marcia Ferraz,Procopio, Jose Valdilanio Virgulino,De Souza, Fabio Santos,MacEdo, Rui Oliveira
, p. 289 - 293 (2010)
This article had studied the thermal characterization of the raw material and different fluconazole crystals, obtained through recrystallization with different solvents using thermoanalytical techniques (TG, DTA, DSC-50, DSC Photovisual, DSC-60) and Pyr-GC/MS. The results confirmed that the fluconazole volatilizes without decomposition until 250 °C. Pyr-GC/MS showed hexachlorobenzene like impurities in fluconazole raw material.
Synthesis of Pyrazines and Quinoxalines via Acceptorless Dehydrogenative Coupling Routes Catalyzed by Manganese Pincer Complexes
Daw, Prosenjit,Kumar, Amit,Espinosa-Jalapa, Noel Angel,Diskin-Posner, Yael,Ben-David, Yehoshoa,Milstein, David
, p. 7734 - 7741 (2018/08/03)
Base-metal catalyzed dehydrogenative self-coupling of 2-amino alcohols to selectively form functionalized 2,5-substituted pyrazine derivatives is presented. Also, 2-substituted quinoxaline derivatives are synthesized by dehydrogenative coupling of 1,2-diaminobenzene and 1,2-diols. In both cases, water and hydrogen gas are formed as the sole byproducts. The reactions are catalyzed by acridine-based pincer complexes of earth-abundant manganese.
Competing Knorr and Fischer-Fink pathways to pyrroles in neutral aqueous solution
Chandrashaker, Vanampally,Taniguchi, Masahiko,Ptaszek, Marcin,Lindsey, Jonathan S.
experimental part, p. 6957 - 6967 (2012/09/07)
A proposed chemical model for the prebiogenesis of tetrapyrrole macrocycles relies on the condensation of a 3-alkyl-substituted 2,4-diketone and an α-aminoketone to form a pyrrole equipped for subsequent self-condensation leading to porphyrinogens. The co