637014-30-3Relevant articles and documents
Diastereodivergent Access to Syn and Anti 3,4-Substituted β-Fluoropyrrolidines: Enhancing or Reversing Substrate Preference
Fjelbye, Kasper,Marigo, Mauro,Clausen, Rasmus Pr?torius,Juhl, Karsten
, p. 1170 - 1173 (2016/03/15)
A practical diastereodivergent access to β-fluoropyrrolidines with two adjacent stereocenters has been demonstrated, by either enhancing or completely reversing the substrate control, in the diastereoselective fluorination of a series of diverse pyrrolidi
PYRROLIDINE DERIVATIVES USEFUL AS BACE INHIBITORS
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Page/Page column 43, (2008/06/13)
Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (= disorder) that depends on the activity of b
A stereoselective approach to both 3,4-trans-disubstituted pyrrolidin-2-ones and pyrrolidines. A convenient synthesis of (3R,4R)-4-benzyl-3-pyrrolidinecarboxylic acid
Galeazzi, Roberta,Martelli, Gianluca,Mobbili, Giovanna,Orena, Mario,Panagiotaki, Maria
, p. 2485 - 2498 (2007/10/03)
Chiral 4-alkyloxymethyl- and silyloxymethylpyrrolidin-2-ones, (10a-c), underwent alkylation to give the corresponding 3,4-trans-disubstituted pyrrolidin-2-ones, (11a-g), in good yield and total stereoselection, as shown by 1H NMR spectral data