637014-31-4Relevant articles and documents
A stereoselective approach to both 3,4-trans-disubstituted pyrrolidin-2-ones and pyrrolidines. A convenient synthesis of (3R,4R)-4-benzyl-3-pyrrolidinecarboxylic acid
Galeazzi, Roberta,Martelli, Gianluca,Mobbili, Giovanna,Orena, Mario,Panagiotaki, Maria
, p. 2485 - 2498 (2007/10/03)
Chiral 4-alkyloxymethyl- and silyloxymethylpyrrolidin-2-ones, (10a-c), underwent alkylation to give the corresponding 3,4-trans-disubstituted pyrrolidin-2-ones, (11a-g), in good yield and total stereoselection, as shown by 1H NMR spectral data