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Diphenyl isobutylphosphoramidate is a chemical compound with the molecular formula C18H20NO2P. It is an organophosphorus compound, specifically a phosphoramidate, which is characterized by the presence of a phosphorus atom bonded to an amide group. diphenyl isobutylphosphoramidate is known for its potential applications in various fields, including as a precursor in the synthesis of other organophosphorus compounds and as a reagent in chemical reactions. It is also of interest in the study of organophosphorus chemistry due to its unique structure and potential reactivity. However, it is important to note that the handling and use of such chemicals should be done with caution, as they can have toxic properties and require proper safety measures.

6372-20-9

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6372-20-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6372-20-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,7 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6372-20:
(6*6)+(5*3)+(4*7)+(3*2)+(2*2)+(1*0)=89
89 % 10 = 9
So 6372-20-9 is a valid CAS Registry Number.

6372-20-9Downstream Products

6372-20-9Relevant academic research and scientific papers

Substitution of diarylphosphoryl azides with aliphatic amines catalyzed by simple rare-earth metal salts: Efficient and novel preparation of phosphoryl amides

Peng, Xin-Hua,Bai, Rui,Liu, Shanshan,Li, Zhuo,Jiao, Lin-Yu

, (2021/11/05)

A novel and high efficient protocol was disclosed herein for the rare-earth metal salt-catalyzed substitution of phosphoryl azides with amines. In this homogeneous catalysis system, different diarylphosphoryl azides and aliphatic and aromatic amines were

When phosphoryl azide meets mechanochemistry: Clean, rapid, and efficient synthesis of phosphoryl amides under B(C6F5)3catalysis in a ball mill

Jia, Nan,Jiao, Lin-Yu,Li, Zhuo,Peng, Xin-Hua,Wang, Ze-Lin

, p. 6659 - 6665 (2021/10/25)

We described herein the first example associated with B(C6F5)3-catalyzed preparation of phosphoryl amides under mechanochemical conditions. In this novel system, the combination of energetic reagents with an energetic mechanochemical process enabled the r

Zinc-catalyzed transformation of diarylphosphoryl azides to diarylphosphate esters and amides

Ying, Jun,Gao, Qian,Wu, Xiao-Feng

supporting information, p. 1540 - 1543 (2020/04/15)

We have developed a facile and efficient procedure for the synthesis of diarylphosphate esters and amides. Using Zn(acac)2 as the catalyst, the reaction of diarylphosphoryl azides with aliphatic alcohols and phenols through an unusual P?N bond cleavage provided a number of diarylphosphate esters in good yields (22 examples, up to 94%). Additionally, various diarylphosphate amides were obtained from the corresponding amines in excellent yields as well (8 examples, up to 96%).

Transition-metal-free amination phosphoryl azide for the synthesis of phosphoramidates

Li, Qing,Sun, Xiaohua,Yang, Xiaoqin,Wu, Minghu,Sun, Shaofa,Chen, Xiuling

, p. 16040 - 16043 (2019/06/10)

A facile and efficient approach to phosphoramidates was developed via amination of phosphoryl azides. A variety of phosphoramidates were obtained in one step with good to excellent yields under a mild reaction system. The process uses easily available ami

Reactivity of cage-like amines toward p-toluenesulfonyl chloride and diphenyl chlorophosphate in acetonitrile

Sadovskii,Solomoichenko,Kas'yan,Golodaeva,Anikanova,Kas'yan,Savelova

, p. 50 - 56 (2007/10/03)

The nucleophilic reactivity of amines of the norbornane, norbornene, and adamantane series toward p-toluenesulfonyl chloride and diphenyl chlorophosphate in acetonitrile at 25°C is determined mainly by the steric factor. Parameters characterizing spatial accessibility of the reaction center in the amine molecule have been determined. Cage-like substituents show no appreciable effect on the amine reactivity, as compared to common alkyl groups.

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