63724-94-7

Upstream product

• 455-13-0 4-Iodobenzotrifluoride 
• 95-15-8 Benzo[b]thiophene 
• 624-31-7 4-tolyl iodide 
• 591-50-4 iodobenzene 

Downstream Products

• 1207-95-0 2-phenylbenzo[b]thiophene 
• 25664-47-5 2-(4-methylphenyl)benzo[b]thiophene 
• 95-15-8 Benzo[b]thiophene 
• 24257-23-6 3-(4-methoxy-phenyl)-benzo[b]thiophene 
• 27884-09-9 2-(4-methoxyphenyl)benzo[b]thiophene 
• 1087352-10-0 (4-(benzo[b]thiophen-2-yl)phenyl)methanol 
• 132932-60-6 2-(p-formylphenyl)benzothiophene 
• 132932-62-8 2-(p-acetylphenyl)benzothiophene 
• 132932-63-9 2-(p-methoxycarbonylphenyl)benzothiophene 
• 936734-96-2 2-(4-fluoro-phenyl)-benzo[b]thiophene 
• 63676-27-7 2-(4-chlorophenyl)-benzo[b]thiophene 
• 19437-86-6 2-(4-bromophenyl)benzo[b]thiophene 
• 54492-94-3 2-(4-nitrophenyl)-benzo[b]thiophene 
• 132932-64-0 2-(p-cyanophenyl)benzothiophene 

Relevant academic research and scientific papers

A general method for copper-catalyzed arylation of arene C-H bonds

A general method for copper-catalyzed arylation of sp2 C-H bonds with pKa's below 35 has been developed. The method employs aryl halide as the coupling partner, lithium alkoxide or K3PO4 base, and DMF, DMPU, or mixed DMF/xylenes solvent. A variety of electron-rich and electron-poor heterocycles such as azoles, caffeine, thiophenes, benzofuran, pyridine oxides, pyridazine, and pyrimidine can be arylated. Furthermore, electron-poor arenes possessing at least two electron-withdrawing groups on a benzene ring can also be arylated. Two arylcopper-phenanthroline complex intermediates were independently synthesized.