63765-74-2

Usage

InChI:InChI=1/C8H8BrNO3/c9-8(10(12)13)7(11)6-4-2-1-3-5-6/h1-5,7-8,11H

Upstream product

• 563-70-2 bromonitromethane 
• 100-52-7 benzaldehyde 

Downstream Products

• 149495-00-1 (S)-1-phenyl-2-nitroethanol 
• 145920-96-3 (R)-2-nitro-1-phenylethanol 
• 141377-54-0 2-nitro-1-phenylethan-1-ol 
• 125787-65-7 N-(1,1-dimethylethyl)-2-hydroxy-benzeneacetamide 

Relevant academic research and scientific papers

Efficient addition reaction of bromonitromethane to aldehydes catalyzed by Nal: A new route to 1-bromo-1-nitroalkan-2-ols under very mild conditions

(Chemical Equation Presented) A catalytic Nal-mediated novel synthesis of 1-bromo-1-nitroalkan-2-ols was carried out by reaction of bromonitromethane with a variety of aldehydes, under very mild conditions. When the reaction was, performed with chiral N,N

Preparation method of mandelamine compound

The invention discloses a preparation method of a mandelamine compound. The preparation method is a complete synthesis method for finally synthesizing a compound with a mandelamine parent by using a benzaldehyde compound as an initiator. An amido bond synthesis part adopts a polarity reversal reaction mechanism of using an amino segment to perform electrophilic attack on an acyl segment. The preparation method can be used for synthesizing multiple compounds which cannot be synthesized by the traditional method.

Indium-mediated debromination of gem -bromonitroalkanes under mild conditions in aqueous medium

gem-Bromonitroalkanes are efficiently reduced into the corresponding dehalogenated products in excellent yields with indium metal in the presence of a palladium(0) catalyst and indium(III) chloride in aqueous medium. The addition of bromonitromethane to c

The guide system, portable electronic equipment and control program

PROBLEM TO BE SOLVED: To provide a leading guide system capable of achieving leading guidance to a destination, using a simple processing. SOLUTION: In the leading guide system 1, tag data of an IC tag 20 embedded in a leading block 10 is read by a guiding stick 30 held by a visually disabled user, and is transmitted to a portable terminal 40. The tag data include a tag ID of the tag, tag IDs and directions of respective adjacent tags along a leading way, and directions of adjacent tags along the leading ways to respective sites proposed. The portable terminal 40 determines the advancing direction of the user, based on the tag data received from the guiding stick 30 the last time and this time; determines a guide direction to the user from the determined advancing direction of the user and the direction of the adjacent tag to the destination; and performs guidance by the sound output. COPYRIGHT: (C)2010,JPOandINPIT

Aqua-aminoorganoboron catalyst: Engineering single water molecule to act as an acid catalyst in nitro aldol reaction

We have disclosed the catalytic potential hidden behind a series of aqua-aminoorganoboron compounds in the formation and reaction of nitronate species. The pivotal role of a single-coordinated water molecule in the catalyst was demonstrated by comparison

A catalytic highly enantioselective direct synthesis of 2-bromo-2-nitroalkan-1-ols through a Henry reaction

Highly enantiomerically enriched 2-bromo-2-nitroalkan-1-ols are prepared by direct condensation of aliphatic and aromatic aldehydes with bromonitromethane in the presence of a catalytic amount of copper(ii) acetate and a C 1-symmetric camphor-d

Fast nitroaldol reaction using powdered KOH in dry media

β-Nitroalkanols are easily obtained within a few minutes, through the nitroaldol (Henry) reaction, catalyzed by a stoichiometric amount of powdered potassium hydroxide, in dry media. Satisfactory to excellent yields are obtained both with primary and seco

Reactions of Salicylaldehydes with Bromonitromethane

Various salicylaldehydes were treated with bromonitromethane in the presence of an inorganic base to give 2-nitrobenzofuran derivatives, and the reaction mechanisms were investigated.The most remarkable feature of the reactions is that 3-hydroxysalicylaldehyde (1k) alone among various hydroxysalicylaldehydes (1b, k, n, r) gave 2-nitro-7-hydroxybenzofuran in good yield.Bromonitromethane reacted with salicylaldehydes at the aldehyde group exclusively to give 1-(2-hydroxyphenyl)-2-bromo-2-nitroethanols (14), followed by cyclization to produce mixtures consisting of cis- and trans-2-nitro-3-hydroxy-2,3-dihydrobenzofurans (8a, b; 9a, b; 10a, b).The stereochemistry of these products is discussed on the basis of the spectral data and chemical reactivities.The intermediates, 2,3-dihydrobenzofurans, underwent dehydration smoothly to give 2-nitrobenzofurans.Keywords - bromonitromethane; salicylaldehyde derivative; ring closure; 2-nitrobenzofuran derivative; cis-2-nitro-3-hydroxy-2,3-dihydrobenzofuran derivative; trans-2-nitro-3-hydroxy-2,3-dihydrobenzofuran derivative; 13C-NMR; stereochemistry; reaction mechanism