637744-49-1

Usage

Uses

Used in Pharmaceutical Applications:
3-fluoro-N-(3,4,5-trifluorobenzyl)aniline serves as a building block in the synthesis of various organic compounds, particularly those with pharmaceutical relevance. Its unique structure and enhanced lipophilicity contribute to the development of new drugs with improved bioavailability and efficacy.
Used in Research Applications:
In the field of research, 3-fluoro-N-(3,4,5-trifluorobenzyl)aniline is utilized as a reagent in chemical reactions, facilitating the synthesis of complex organic molecules. Its unique properties allow for the exploration of novel chemical pathways and the discovery of new compounds with potential applications in various industries.
Used in Chemical Reactions:
3-fluoro-N-(3,4,5-trifluorobenzyl)aniline is employed as a reagent in various chemical reactions, enabling the formation of new compounds with specific properties. Its fluorinated structure can influence the reaction outcomes, leading to the development of innovative materials and products.
Used in Controlled Laboratory Environments:
Due to its potential toxicity and reactive nature, 3-fluoro-N-(3,4,5-trifluorobenzyl)aniline is primarily used in controlled laboratory environments. Researchers and chemists handle the compound with caution, ensuring safety protocols are followed to minimize risks associated with its use.

Upstream product

• 372-19-0 meta-fluoroaniline 
• 132123-54-7 3,4,5-trifluorobenzaldehyde 
• 220141-72-0 3,4,5-trifluorobenzyl bromide 
• 1202493-05-7 C₁₃H₇F₄N 

Downstream Products

• 637744-48-0 (3-fluorophenyl)(3,4,5-trifluorobenzyl)carbamoyl chloride 
• 385367-47-5 Tarafenacin 
• 637744-70-8 (3R)-3-[(3-fluorophenyl)(3,4,5-trifluorobenzyl)carbamoyloxy]-1-(2-phenoxyethyl)-1-azoniacyclo[2.2.2]octane bromide 

Relevant academic research and scientific papers

Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinyl carbamates as potent and long acting muscarinic antagonists

Novel quaternary ammonium derivatives of N,N-disubstituted (3R)-quinuclidinyl carbamates have been identified as potent M3 muscarinic antagonists with long duration of action in an in vivo model of bronchoconstriction. These compounds have also presented a high level of metabolic transformation (human liver microsomes). The synthesis, structure-activity relationships and biological evaluation of these compounds are reported.

Stable crystalline salt of (R)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester

The present invention refers to a stable crystalline salt of (R)-3-fluorophenyl- 3,4,5-trifluorobenzylcarbamic acid 1-azabicyclo [2.2.2]oct-3-yl ester of formula (I) and its use as medicament, in particular for the treatment of urinary incontinence or oth

NOVEL QUINUCLIDINE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME

Carbamates of formula (I) or pharmaceutically acceptable salts thereof, including quaternary ammonium salts of formula (II) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as antagonists of M3 muscarinic receptors.