63806-52-0Relevant academic research and scientific papers
Gold Catalyzed Synthesis of Substituted Furan by Intermolecular Cascade Reaction of Propargyl Alcohol and Alkyne
Hosseyni, Seyedmorteza,Su, Yijin,Shi, Xiaodong
supporting information, p. 6010 - 6013 (2016/01/09)
Using a combination of triazole-gold (TA-Au) and copper catalysts, the substituted furan was achieved in one pot through a three-step reaction cascade. The reaction tolerates a large substrate scope with simple starting materials. The desired di-, tri-, and tetrasubstituted furans were prepared in good to excellent yields.
Thermolysis of selenophene 1,1-dioxides
Umezawa, Takashi,Matsui, Tomoki,Sugihara, Yoshiaki,Ishii, Akihiko,Nakayama, Juzo
, p. 61 - 69 (2007/10/03)
Selenophene 1,1-dioxides are thermally far labile than the corresponding thiophene 1,1-dioxides. Even heavily substituted tetraphenylselenophene 1,1-dioxide (1a) decomposed, by a process not involving cyclodimerization, when heated above its melting point or heated in refluxing toluene. Thus, the thermolysis of la in refluxing toluene afforded tetraphenylselenophene (2a, 6%), tetraphenylfuran (3a, 71%), (Z)-l,2,3,4-tetraphenyl-2-butene-l,4-dione (Z-4a, 19%), (E)-1,2,3,4-tetraphenyl-2-butene-1,4-dione (E-4a, 4%), SeO2 (23%), and Se (22%), while that of the neat sample gave 2a (5%), Z-4a (78%), E-4a (17%), SeO2 (17%), and Se (29%). Similar results were also obtained on thermolyses of a series of selenophene 1,1-dioxides. The experimental observations (influence of solvents, oxygen, and additive such as diene to the decomposition rate and the presence of induction period) revealed that the mechanism of the decomposition is highly complex. A tentative mechanism that can explain the observed products is presented.
SYNTHESIS OF FURANS BY ACYLATION OF CYCLOPROPENES
Bartmann, Ekkehard,Gompper, Rudolf
, p. 263 - 270 (2007/10/02)
Cyclopropenes substituted with phenyl groups at the double bond react with acyl chlorides in the presence of aluminium chloride under formation of phenyl substituted furans.
A New and Versatile Synthesis of Furans
Koenig, Horst,Graf, Fritz,Weberndoerfer, Volkmar
, p. 668 - 682 (2007/10/02)
The thermal reaction of oxazoles 1 and acetylenic dienophiles 2 provides a synthetic approach to a great variety of furans (Table 1).Scope and mechanism of this reaction are discussed.Biologically active substances of type 7 are described as examples for practical application.
