63816-18-2

Usage

Uses

Used in Pharmaceutical Industry:
6-Chloro-2-methyl-benzoxazole is used as an intermediate in the synthesis of various pharmaceuticals for its wide range of chemical reactivity and potential biological and pharmacological activities.
Used in Agrochemical Industry:
This benzoxazole derivative is utilized as an intermediate in the synthesis of agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Dye Industry:
6-Chloro-2-methyl-benzoxazole is employed in the synthesis of dyes, where its chemical properties are leveraged to create a variety of colorants for different applications.
Used in Organic Synthesis Processes:
Due to its versatile chemical reactivity, 6-chloro-2-methyl-benzoxazole is used in various organic synthesis processes to produce a range of chemical compounds for diverse applications across industries.

InChI:InChI=1/C8H6ClNO/c1-5-10-7-3-2-6(9)4-8(7)11-5/h2-4H,1H3

Upstream product

• 28443-50-7 2-amino-5-chlorophenol 
• 123-54-6 acetylacetone 
• 16323-09-4 N-(4-chloro-2-hydroxyphenyl)acetamide 
• 3296-05-7 1-azido-4-chlorobenzene 
• 64-19-7 acetic acid 

Relevant academic research and scientific papers

Synthesis of benzoxazoles from 2-aminophenols and β-diketones using a combined catalyst of br?nsted acid and copper iodide

Cyclization reactions of 2-aminophenols with β-diketones catalyzed by a combination of Br?nsted acid and CuI are presented. Various 2-substituted benzoxazoles were obtained through these reactions. Different substituents such as methyl, chloro, bromo, nitro, and methoxy on 2-aminophenol are tolerated under the optimized reaction conditions.

Reexamination of the Thermolytic Rearrangement of 4-Halophenyl Azides to 2-Aminophenols and other Products

The halogenation of derivatives of 2-aminophenol with N-chloro- and N-bromosuccinimides at ambient temperatures in acetic acid was studied.With the necessary compounds available, a reexamination of the thermolytic rearrangement of 2-halophenyl azides to 2-aminophenols and other products was undertaken.It is certain that the rearrangement of 4-halophenyl azides to 2-aminophenols occurs but the products identified in this study differ significantly from those reported previously by Suschitzky et al. (1963, 1966). Keywords: Acetylated-2-amino-5-halophenols; 2-Acetamido-5-haloanisoles; 6-Halo-2-methylbenzoxazoles; 6-Halobenzoxazolones; 6-Halotriacetylaminophenols; 1H-NMR spectra; Fungicidal activity.