63816-18-2 Usage
General Description
6-Chloro-2-methyl-benzoxazole is a chemical compound with the molecular formula C8H6ClNO. It is a benzoxazole derivative that contains a chlorine atom and a methyl group attached to the benzene ring. 6-CHLORO-2-METHYL-BENZOXAZOLE is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It has also been studied for its potential biological and pharmacological activities. As a benzoxazole derivative, it exhibits a wide range of chemical reactivity and is utilized in various organic synthesis processes. Additionally, it is important to handle this chemical compound with caution and in accordance with proper safety protocols due to its potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 63816-18-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,8,1 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 63816-18:
(7*6)+(6*3)+(5*8)+(4*1)+(3*6)+(2*1)+(1*8)=132
132 % 10 = 2
So 63816-18-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H6ClNO/c1-5-10-7-3-2-6(9)4-8(7)11-5/h2-4H,1H3
63816-18-2Relevant articles and documents
Synthesis of benzoxazoles from 2-aminophenols and β-diketones using a combined catalyst of br?nsted acid and copper iodide
Mayo, Muhammad Shareef,Yu, Xiaoqiang,Zhou, Xiaoyu,Feng, Xiujuan,Yamamoto, Yoshinori,Bao, Ming
, p. 6310 - 6314 (2014/07/21)
Cyclization reactions of 2-aminophenols with β-diketones catalyzed by a combination of Br?nsted acid and CuI are presented. Various 2-substituted benzoxazoles were obtained through these reactions. Different substituents such as methyl, chloro, bromo, nitro, and methoxy on 2-aminophenol are tolerated under the optimized reaction conditions.