63834-83-3

Usage

Uses

Used in Cancer Therapy:
Guaietolin is used as an anticancer agent for its ability to inhibit the growth of cancer cells and induce apoptosis. It has potential applications in the development of new cancer therapies.
Used in Antioxidant Applications:
Guaietolin is used as an antioxidant for its ability to combat oxidative stress, making it a promising compound for the treatment of oxidative stress-related diseases.
Used in Anti-inflammatory Applications:
Guaietolin is used as an anti-inflammatory agent for its ability to reduce inflammation, making it a potential treatment for inflammatory conditions.

InChI:InChI=1/C11H16O4/c1-2-14-10-5-3-4-6-11(10)15-8-9(13)7-12/h3-6,9,12-13H,2,7-8H2,1H3

Upstream product

• 74-96-4 ethyl bromide 
• 19826-87-0 3-(2-hydroxy-phenoxy)-propane-1,2-diol 
• 94-71-3 2-Ethoxyphenol 
• 96-24-2 3-monochloro-1,2-propanediol 
• 556-52-5 oxiranyl-methanol 
• 120-80-9 benzene-1,2-diol 

Downstream Products

• 137208-72-1 Sulfamic acid 3-(2-ethoxyphenoxy)-1,2-propanediyl ester 
• 137208-76-5 Methylsulfamic acid 3-(2-ethoxyphenoxy)-1,2-propanediyl ester 

Relevant academic research and scientific papers

Spontaneous resolution among chiral glycerol derivatives: crystallization features of ortho-alkoxysubstituted phenyl glycerol ethers

Five chiral arylglycerol ethers 2-R-C6H4-O-CH2CH(OH)CH2OH (R = OMe, OEt, OPrn, OPri, OBut) have been prepared in racemic and enantiopure form. The melting points and enthalpies of fusion of every species were measured by differential scanning calorimetry. Binary phase diagrams were reconstructed for the whole family, the entropies of the mixing of the enantiomers in the liquid state, and Gibbs free energy of formation of the racemic compound, as well as Pettersson i-values were derived from the thermal data. The differences in the phase behavior of the investigated compounds were associated with the conformations of the alkoxy fragments.

Sulfamates as antiglaucoma agents

Sulfamate esters of the formula where A is aryloxyalkyl, p is the number of unreacted hydroxy groups present on the alkyl moiety and may be zero, z is the number of --OS(O)2 NR1 R2 groups attached to carbons of the alkyl moiety and is always at least one; R1 and R2 are selected from hydrogen, loweralkyl, carboxy, and the like are useful in treating glaucoma.

Compounds having one or more aminosulfaonyloxy radicals useful as pharmaceuticals

Methods of treating chronic arthritis and osteoporosis which utilize both known and novel compounds which would fall under the general formula:(HO)p--A--[--OS(O) 2 NR 1 R 2 ] zwherein A encompasses a wide range of values including but not limited to aryl, loweralkyl, cycloalkyl, and carbohydrates including sucrose and fructose; p is equal to the number of unreacted hydroxy groups contained on the molecule and may be zero; z is the number of --OS(O) 2 NR 1 R 2 groups and is always at least one; R 1 and R 2 are selected from hydrogen, loweralkyl, carboxy and the like; a novel process for preparing the compounds is provided wherein an appropriate sulfamic acid aryl ester is reacted with a hydroxy substituted A radical which may or may not contain thereon protected carboxyl, amino or hydroxy substituents, in an aprotic solvent containing a tertiary amine base. Pharmaceutical compositions for the treatment of chronic arthritis and osteoporosis are also provided.