63853-81-6Relevant articles and documents
Photolytic Dehydrochlorination of N-Chloro-N-alkyl Amides: Formaton of N-(α-Methoxyalkyl) Amides
Phan, Xuan T.,Shannon, Paul J.
, p. 5164 - 5170 (2007/10/02)
The photoinduced dehydrochlorination, in methanol, of N-chloro-N-alkyl amides with one substitient at the α position to nitrogen gave good yields of N-(α-methoxyalkyl) amides and the parent amides as secondary products.N-Chloro amides disubstituted at the α position gave mostly parent amides.In most cases no products resulting from 1,5 hydrogen transfer of amidyl radicals were observed.The quantum yields of decomposition of N-chloro-N-methylpentanamide (1a) were significantly greater than unity, indicative of a chain process for dehydrochlorination.The reaction was affected by the solvent, addition of base or radical inhibitors, concentration of N-chloro amide, light intensity, and irradiation wavelenght.
