6391-98-6Relevant academic research and scientific papers
Method for promoting elemental sulfur to synthesize thioamide by mixed alkali in water phase
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Paragraph 0053-0056, (2020/07/13)
The invention provides a method for promoting elemental sulfur to synthesize a thioamide compound by a mixed alkali in a water phase, and belongs to the field of organic synthesis. According to the method, an aldehyde compound and an amide compound are us
Mixed bases mediated synthesis of thioamides in water
Li, Jiao,Ren, Xuanhe,Li, Ganzhong,Liang, Helong,Zhao, Yajie,Wang, Zhiwu,Li, Heng,Yuan, Bingxin
, p. 229 - 237 (2020/02/20)
A mixed bases mediated protocol is developed to synthesize thioamides from N-aryl or N-alkylamide, aldehyde and elemental sulfur in water. This reaction requires no addition of external oxidant and avoids large excess of amides. Various functional groups
Rhodamine inhibitors of P-glycoprotein: An amide/thioamide "switch" for ATPase activity
Gannon II, Michael K.,Holt, Jason J.,Bennett, Stephanie M.,Wetzel, Bryan R.,Loo, Tip W.,Bartlett, M. Claire,Clarke, David M.,Sawada, Geri A.,Higgins, J. William,Tombline, Gregory,Raub, Thomas J.,Detty, Michael R.
experimental part, p. 3328 - 3341 (2010/03/26)
We have examined 46 tetramethylrosamine/rhodamine derivatives with structural diversity in the heteroatom of the xanthylium core, the amino substituents of the 3- and 6-positions, and the alkyl, aryl, or heteroaryl group at the 9-substituent. These compou
The Willgerodt-Kindler reaction in water: High chemoselectivity of benzaldehydes over acetophenones
Aghapoor, Kioumars,Mohsenzadeh, Farshid,Khanalizadeh, Golriz,Darabi, Hossein R.
, p. 61 - 65 (2007/10/03)
Water has been found for the first time as a useful solvent in the Willgerodt-Kindler (WK) reaction for the synthesis of benzothiomorpholides in high yield at 80°C for 3 h. This novel approach confronts the WK protocol with a new situation in which water
The reaction of α-amino-substituted diphenylphosphine oxide anions with elemental sulfur and selenium. A new route to thio- and selenoamides
Otten, P. A.,Gen, A. van der
, p. 499 - 506 (2007/10/02)
The lithiated anions of α-amino-substituted diphenylphosphine oxides 1, in which R can be hydrogen, aryl, alkyl and alkenyl, react with two equivalents of sulfur or selenium to form thio- and selenoamides, which can be isolated in good to excellent yields
