639482-02-3

Basic information

• Product Name: pentafluorophenyl 3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridine-2-carboxylate
• Synonyms: pentafluorophenyl 3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridine-2-carboxylate
• CAS NO: 639482-02-3
• Molecular Weight: 564.44
• Mol File: 639482-02-3.mol

Chemical Properties

• CAS DataBase Reference: pentafluorophenyl 3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: pentafluorophenyl 3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridine-2-carboxylate(639482-02-3)
• EPA Substance Registry System: pentafluorophenyl 3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridine-2-carboxylate(639482-02-3)

Safety Data

• Hazardous Substances Data: 639482-02-3(Hazardous Substances Data)

Upstream product

• 816424-66-5 lithium 3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridine-2-carboxylate 
• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 639481-91-7 ammonium 3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridine-2-carboxylate 
• 52505-46-1 ethyl 3-aminothieno[2,3-b]pyridine-2-carboxylate 
• 514182-52-6 ethyl [3-bromo-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-2-carboxylate] 
• 514182-48-0 ethyl 3-bromothieno[2,3-b]pyridine-2-carboxylate N-oxide 
• 72832-23-6 ethyl 3-bromothieno(2,3-b)pyridine-2-carboxylate 
• 514182-57-1 3-bromo-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridine-2-carboxylic acid ethyl ester 
• 6602-54-6 2-chloro-3-pyridinecarbonitrile 

Downstream Products

• 816464-41-2 tert-butyl (3R)-3-[({3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridin-2-yl}carbonyl)amino]pyrrolidine-1-carboxylate 
• 816464-54-7 3-[(2,4-difluorophenyl)amino]-N-[(1S,2S)-2-hydroxycyclopentyl]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridine-2-carboxamide 
• 816424-31-4 2-{[(3R)-3-aminopyrrolidin-1-yl]carbonyl}-3-[(2,4-difluorophenyl)amino]-7-phenylthieno[2,3-b]pyridin-6(7H)-one 
• 816426-21-8 3-[(2,4-difluorophenyl)amino]-2-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}-7-phenylthieno[2,3-b]pyridin-6(7H)-one 
• 816424-18-7 3-[(2,4-difluorophenyl)amino]-2-{[(3S)-3-hydroxypyrrolidin-1-yl]carbonyl}-7-phenylthieno[2,3-b]pyridin-6(7H)-one 
• 816425-16-8 tert-butyl [1-({3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridin-2-yl}carbonyl)piperidin-4yl]carbamate 
• 639481-27-9 3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-N-pyrrolidin-3-yl-6,7-dihydrothieno[2,3-b]pyridine-2-carboxamide 
• 816464-63-8 3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-N-(piperidin-4-yl)-6,7-dihydrothieno[2,3-b]pyridine-2-carboxamide 
• 816464-56-9 3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-N-[(3R)-pyrrolidinyl-3-yl]-6,7-dihydrothieno[2,3-b]-2-carboxamide 
• 816424-44-9 rac-2-{[-3-aminopyrrolidin-1-yl]carbonyl}-3-[(2,4-difluorophenyl)amino]-7-phenylthieno[2,3-b]pyridin-6(7H)-one 
• 816424-45-0 2-{[(3S)-3-aminopyrrolidin-1-yl]carbonyl}-3-[(2,4-difluorophenyl)amino]-7-phenylthieno[2,3-b]pyridin-6(7H)-one 
• 816424-95-0 tert-butyl [(3S)-1-({3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridin-2-yl}carbonyl)pyrrolidin-3-yl]carbamate 
• 816424-19-8 3-[(2,4-difluorophenyl)amino]-2-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-7-phenylthieno[2,3-b]pyridin-6(7H)-one 
• 816424-94-9 rac-tert-butyl [1-({3-[(2,4-difluorophenyl)amino]-6-oxo-7-phenyl-6,7-dihydrothieno[2,3-b]pyridin-2-yl}carbonyl)pyrrolidin-3-yl]carbamate 

Relevant articles and documents

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THIENOPYRIDONE DERIVATIVES AS KINASE INHIBITORS

A series of thieno[2,3-b]pyridin-6(7H)-one derivatives, substituted in the 2-position by a carbonyl- or sulfonyl-linked pyrrolidin-1-yl or related moiety, being inhibitors of p38 MAP kinase, are accordingly of use in medicine, for example in the treatment

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