6396-07-2

Basic information

• Product Name: DIIODOTRIPHENYLPHOSPHORANE
• Synonyms: DIIDOTRIPHENYLPHOSPHORANE;DIIODOTRIPHENYLPHOSPHORANE;TRIPHENYLPHOSPHINE DIIODIDE;diiodotriphenyl-phosphoran;iodotriphenylphosphoraniumiodide;DIIODOTRIPHENYLPHOSPHORANE, TECH., 90%;Triphenyldiiodophosphorane;diiodo(triphenyl)-$l^{5}-phosphane
• CAS NO: 6396-07-2
• Molecular Formula: C₁₈H₁₅I₂P
• Molecular Weight: 516.09
• Mol File: 6396-07-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: 210-220 °C(lit.)
• Appearance: Yellow to orange/Powder
• Storage Temp.: 2-8°C
• Sensitive: Light Sensitive
• CAS DataBase Reference: DIIODOTRIPHENYLPHOSPHORANE(CAS DataBase Reference)
• NIST Chemistry Reference: DIIODOTRIPHENYLPHOSPHORANE(6396-07-2)
• EPA Substance Registry System: DIIODOTRIPHENYLPHOSPHORANE(6396-07-2)

Safety Data

• Hazard Codes: C
• Statements: 34-42/43-62
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2923 8/PG 2
• WGK Germany: 3
• RTECS: TB6100000
• F: 8-10
• HazardClass: 8
• Hazardous Substances Data: 6396-07-2(Hazardous Substances Data)

Usage

Uses

Triphenylphosphine diiodide (Ph3P. I2) can be used as a reagent: To facilitate the conversion of alcohol, thiol, and enol functional groups into alkyl iodides via formation of alkoxyphosphonium iodide. To prepare β-iodo-α,β-unsaturated ketones from cyclic β-diketones in the presence of triethyl amine. In the synthesis of alkyl nitrates from alcohols. In the Beckmann rearrangement reaction to synthesize lactams from cycloalkanone oxime. For the preparation of aromatic and aliphatic carboxylic acid esters in the presence of N,N-dimethylaminopyridine. Ph3P. I2 can also be used to reduce graphene oxide for the production of graphene nanosheets under mild and environmentally friendly conditions.

InChI:InChI=1/C18H15I2P/c19-21(20,16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H

Upstream product

• 16029-98-4 trimethylsilyl iodide 
• 2526-64-9 dichlorotriphenylphosphorane 
• 2065-67-0 tetraphenylphosphonium iodide 
• 1034-39-5 dibromotriphenylphosphorane 
• 603-35-0 triphenylphosphine 
• 93374-06-2 tetraethylphosphorodiamidothioic iodide 
• 54305-75-8 N,N-diethylaminodiiodophosphine 
• 2588-88-7 pentaphenylphosphorane 

Downstream Products

• 181784-19-0 InI₃(P(C₆H₅)3)*InI₃(P(C₆H₅)3)2 
• 1198298-17-7 CpCr[(2,6-Me₂C₆H₃NCMe)2CH](I) 
• 705298-27-7 [Fe(η(2)-OCNiPr2)(CO)2(PPh3)2]BF4 
• 603-35-0 triphenylphosphine 
• 791-28-6 Triphenylphosphine oxide 
• 164072-11-1 Fe(CO)2I(triphenylphosphine)(η(2)-O=CN((i)Pr)2) 
• 149831-14-1 [(C₆H₅)3PI][Co(P(C₆H₅)3)I₃], bright green 
• 149831-14-1 {P(C₆H₅)3I}⁽¹⁺⁾*{CoP(C₆H₅)3I₃}^(1-)={P(C₆H₅)3I}{CoP(C₆H₅)3I₃} 
• 152442-02-9 {(C₆H₅)3PI}⁽¹⁺⁾*{Ni(P(C₆H₅)3)I₃}^(1-)={(C₆H₅)3PI}{Ni(P(C₆H₅)3)I₃} 
• 14057-04-6 diiodobis(triphenylphosphine)zinc 
• 10139-47-6 zinc(II) iodide 
• 7790-33-2 manganese(II) iodide 
• 23661-58-7 MnI₂(P(C₆H₅)3)2 
• 845-64-7 triphenyldifluorophosphorane 

Relevant articles and documents

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Halogenation through Deoxygenation of Alcohols and Aldehydes

An efficient reagent system, Ph3P/XCH2CH2X (X = Cl, Br, or I), was very effective for the deoxygenative halogenation (including fluorination) of alcohols (including tertiary alcohols) and aldehydes. The easily available 1,2-dihaloethanes were used as key reagents and halogen sources. The use of (EtO)3P instead of Ph3P could also realize deoxy-halogenation, allowing for a convenient purification process, as the byproduct (EtO)3Pa?O could be removed by aqueous washing. The mild reaction conditions, wide substrate scope, and wide availability of 1,2-dihaloethanes make this protocol attractive for the synthesis of halogenated compounds.

SPIRO(5.5)UNDECANE DERIVATIVES

The invention relates to compounds that have an affinity to the μ-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.