63969-83-5

Basic information

• Product Name: methyl 2-(2-formylphenyl)acetate
• Synonyms: methyl 2-(2-formylphenyl)acetate;Methyl 2-(2-formylphenyl)
• CAS NO: 63969-83-5
• Molecular Formula: C₁₀H₁₀O₃
• Molecular Weight: 178.186
• Mol File: 63969-83-5.mol

Chemical Properties

• Boiling Point: 273.9 °C at 760 mmHg
• Flash Point: 117.5 °C
• Appearance: /
• Density: 1.157
• Vapor Pressure: 0.00559mmHg at 25°C
• Refractive Index: 1.549
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: Chloroform (Slightly)
• Stability: Air Sensitive
• CAS DataBase Reference: methyl 2-(2-formylphenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2-formylphenyl)acetate(63969-83-5)
• EPA Substance Registry System: methyl 2-(2-formylphenyl)acetate(63969-83-5)

Safety Data

• Hazardous Substances Data: 63969-83-5(Hazardous Substances Data)

Usage

Uses

Used in Fragrance and Flavor Industry:
Methyl 2-(2-formylphenyl)acetate is used as a fragrance ingredient for its sweet and floral scent, adding pleasant aromas to various products.
Used in Cosmetic and Personal Care Products:
In the cosmetic and personal care industry, methyl 2-(2-formylphenyl)acetate is used as a flavoring agent to enhance the taste and smell of products, contributing to a more enjoyable consumer experience.
Used in Food and Beverage Flavorings:
Methyl 2-(2-formylphenyl)acetate is employed as a flavor enhancer in the food and beverage industry, imparting a desirable taste and aroma to a range of products.

InChI:InChI=1/C10H10O3/c1-13-10(12)6-8-4-2-3-5-9(8)7-11/h2-5,7H,6H2,1H3

Upstream product

• 67-56-1 methanol 
• 1723-55-3 ortho-formylphenylacetic acid 
• 13737-37-6 methyl 2-[2-(bromomethyl)phenyl]acetate 
• 644-36-0 o-methylphenylacetic acid 
• 29810-10-4 methyl α-(N,N-dimethylamino)phenylacetate 
• 1358418-45-7 methyl α-(N-cyanomethyl-N-methylamino)phenylacetate 
• 1358418-47-9 2-(methoxycarbonylmethyl)-α-(dimethylamino)phenylacetonitrile 
• 1358418-57-1 N-cyanomethyl-N,N-dimethyl-N-(α-methoxycarbonylbenzyl)ammonium trifluoromethanesulfonate 
• 1358418-55-9 N-cyanomethyl-N,N-dimethyl-N-(α-methoxycarbonylbenzyl)ammonium methylsulfate 
• 1358418-50-4 N-cyanomethyl-N,N-dimethyl-N-(α-methoxycarbonylbenzyl)ammonium bromide 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 

Downstream Products

• 116206-45-2 Methyl 2-<3-oxo-4-(3-chlorophenoxy)-1E-butenyl>phenylacetate 
• 116206-43-0 2-(3-oxo-1E-octenyl)phenylacetic acid methyl ester 
• 6772-73-2 1,4-dihydro-2-(phenylmethyl)-3(2H)-isoquinolinone 
• 24331-94-0 1,4-dihydro-3(2H)-isoquinolinone 

Relevant articles and documents

Photochemistry of 1,3-bis(diazo)indan-2-one: Consecutive decomposition and suppression of a Wolff rearrangement

The photodecomposition processes of 1,3-bis(diazo)indan-2-one (19) have been investigated by the characterization of reaction products in fluid solutions and by the direct observation of reactive intermediates in matrices at cryogenic temperatures. Irradi

Approach to Chiral 1-Substituted Isoquinolone and 3-Substituted Isoindolin-1-one by Addition-Cyclization Process

An approach to access 1-substituted isoquinolones has been developed through the addition-cyclization of imines with Grignard reagents in the presence of 2,2′-dipyridyl. A number of substituted aromatic magnesium reagents were amenable to this process, and the desired products were obtained with excellent yields and outstanding diastereoselectivities (dr > 99:1). The utility of this convenient approach is demonstrated by the formal synthesis of (S)-cryptostyline II. Moreover, N-methylmorpholine (NMM) was found to be an effective additive for the formation of 3-substituted isoindolin-1-ones using one-pot addition-cyclization-deprotection of imine with Grignard reagents.

Sigmatropic rearrangement of ammonium ylideskey step in the synthesis of methyl 2-formylphenyl acetate

N-Cyanomethyl-N,N-dimethyl-N-(-methoxycarbonyl)benzylammonium salts 5 were synthesized and treated with different base/solvent systems, giving the products of sigmatropic rearrangements [2,3] 7 and [1,2] 8. In reactions carried out in liquid ammonia, [2,3] rearrangement definitively prevailed. Pure 7(or mixture of 7 and 8) were deprotected to afford methyl 2-formylphenyl acetate (9) in good yield.

Methyl α-arylacrylates substituted by a heterocyclic radical and their use

Methyl α-arylacrylates substituted by a heterocyclic radical and having the general formula STR1 where R is alkyl, alkenyl, haloalkyl, cycloalkyl, alkoxy, alkylcarbonyl, alkoxycarbonyl, halogen or aryl, the aromatic ring being unsubstituted or substituted, Het is a five-membered heteroaromatic ring which is unsubstituted or substituted and has from one to three heteroatoms, and A is ethenylene, ethylene, methyleneoxy or methylenethio, and fungicides and pesticides containing these compounds.

PROSTANOIDS. SYNTHESIS OF &α-PENTANORBENZO ANALOGS OF PROSTAGLANDINS

The α-pentanorbenzo analogs of prostaglandins were synthesized from o-formylphenylacetic acid, which was obtained by the ozonization of indene under specific conditions.